沉淀法原位复合聚乙烯醇(PVA)/羟基磷灰石(HA)水凝胶的结构与性能研究  

The Compounding in situ by precipitation of Poly(vinyl alcohol) Hydrogel with Hydroxyapatite and Investigation on the Structure and Properties

作　　者：王迎军[1] 刘青[1] 郑裕东[2] 吴刚[1] 

机构地区：[1]华南理工大学材料学院,广州510641 [2]北京科技大学材料学院,北京100083

出　　处：《中国生物医学工程学报》2005年第2期150-153,共4页Chinese Journal of Biomedical Engineering

基　　金：国家自然科学基金重点资助项目 (5 993 2 0 5 0 ) ;广东省自然科学基金资助项目 (990 62 1) ;广东省十五攻关重大专项 (A0 3 0 2 0 2 0 2 0 2 )。

摘　　要：研究了制备聚乙烯醇 (PVA) / 羟基磷灰石 (HA)复合水凝胶的沉淀法原位复合技术 ,对该法制备的复合水凝胶的力学强度、结晶性能和微观形貌进行了分析 ,并与物理共混法加以比较。结果表明 ,沉淀法原位复合技术可在PVA水凝胶基体中合成得到粒度细 ,分散好的晶相HA陶瓷微粒 ,复合后水凝胶的结晶度和拉伸强度比之基体试样均有大幅度提高。In this paper, the compounding in situ by precipitation to prepare Poly(vinyl alcohol)/Hydroxyapatite compound hydrogel was investigated. The tensile strength, crystallinity, and micromorphology of compound hydrogel were measured and observed. It was founded that the compounding in situ by precipitation can obtain ultrafine granular-crystalline of HA dispersed evenly in matrix compared with mechanical mix method. The crystallinity and tensile strength of compound hydrogel were highly increased.

关 键 词：羟基磷灰石(HA) 聚乙烯醇 沉淀法 原位复合 性能研究 复合水凝胶 结构 复合技术 微观形貌 物理共混 结晶性能 力学强度 PVA 强度比 结晶度 基体 制备 

分 类 号：R779.64[医药卫生—眼科] R318.08[医药卫生—临床医学]