国人英文语言活动区功能磁共振研究  

A fMRI Study of English Cerebral Representation in Chinese-English Bilinguals

作　　者：赵小虎[1] 杨振燕[1] 王培军[1] 王金红[1] 毛新清[1] 高晓龙[1] 

机构地区：[1]同济大学附属同济医院医学影像科,上海200065

出　　处：《同济大学学报（医学版）》2005年第2期38-40,52,共4页Journal of Tongji University(Medical Science)

基　　金：浙江大学"2 11工程"重点学科建设项目 (10 72 0 0 -2 2 1181) .

摘　　要：目的　利用BOLD功能磁共振,初步探索母语为中文者,说第二语言(L2 )英文时大脑的语言相关功能区。方法　对2 2名“晚双语”正常中国人,说英文句子状态下进行BOLD磁共振脑功能成像,探索其L2大脑活动皮层相关功能区。结果　说英文时激活的脑区包括:左右侧运动区、左额下回、右额下回、左侧颞上回、岛叶及左右侧小脑。结论　BOLD功能磁共振可显示第二语言英文大脑活动相关皮层,是无创性研究人类语言的有力武器。Objective To investigate the brain areas asso ciated with Chinese-English bilinguals when they speak English(L2). Methods In order to determine the neural anatomic substra tes employed in repeatedly speaking English,22 Chinese healthy volunteers were p erformed in this study by using blood oxygenation level dependent (BOLD) contras t functional magnetic resonance imaging (fMRI) on a 1.5T system. Results Our block-design fMRI studies had found many cor tic areas that were associated with Chinese-English bilinguals.Those cortic are as were:left motor cortex,left posterior inferior frontal gyrus,left superior te mporal gyrus,left anterior insula and bilateral cerebellum. Conclusion BOLD fMRI can reveal cortic areas that are ass ociated with Chinese-English bilinguals when they speak English (L2),and it mig ht be a powerful utility to engage language research without trauma.

关 键 词：语言 英文 功能MRI 说话 血氧水平依赖性 

分 类 号：R338.8[医药卫生—人体生理学] R445.2[医药卫生—基础医学]