正常及病变角膜光学相干断层扫描观察  

Imaging of normal and pathological cornea by optical coherence tomography

作　　者：梁丽娜[1] 侯静[1] 袁敏立[1] 唐由之[1] 

机构地区：[1]中国中医研究院眼科医院,北京100040

出　　处：《中国中医眼科杂志》2005年第2期63-65,共3页China Journal of Chinese Ophthalmology

摘　　要：目的观察正常及病理状态下角膜的光学相干断层成像特征。方法对40例正常人角膜进行OCT检查,观察正常人群的角膜成像特征并测量中央角膜厚度;同时检查3位角膜病变患者,观察角膜白斑、角膜炎,角膜基质水肿的OCT特征。结果40位正常人中央角膜平均厚度平均为549.16μm±15.16μm。其中男性平均值550.18μm±13.03μm,女性平均值547.96μm±16.09μm,两者相比差异无显著性(P】0.05);OCT下角膜白斑、角膜炎,角膜基质水肿等病变表现出不同的形态学特征,与裂隙灯下观察的病变相符合。结论OCT可以作为角膜厚度测量和病变观察的有效手段。OBJECTIVE To demonstrate the capability of optical coherence tomography(OCT)device to imagine human normal and pathological cornea in vivo and to measure central cornea thickness(CCT) in normal cornea.METHODS CCT measured by OCT were obtained in 75 normal eyes of 40 subject.And three pathological corneas including cornea scar,keratitis,and cornea edema were observed with OCT.RESULTS In normal subjects CCT was 549.16μm±15.16μm,and there was no significant difference between males and females.Under OCT observation,Cornea scar,keratitis,cornea edema showed different characters,which correlated well with their characters under slim lamp.CONCLUSION OCT could be an useful method for measurement of CCT and observation of cornea disease.

关 键 词：光学相干断层扫描 角膜 中央角膜厚度 

分 类 号：R770.43[医药卫生—眼科]