ROU患者唾液和血清免疫球蛋白变化的观察  

Observation of changes of saliva and serum Immumoglobulins in recurrent aphthae Patients

作　　者：吴慧华[1] 王燕秋[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院口腔医学中心,湖北武汉430030

出　　处：《临床口腔医学杂志》2005年第5期308-309,共2页Journal of Clinical Stomatology

摘　　要：目的:了解复发性口疮(ROU)发病与免疫的关系。方法:通过测定复发性口疮患者唾液SIgA、IgG、溶菌酶的活性以及血清免疫球蛋白、C3的含量,并与正常对照组进行比较。结果:复发性口疮患者唾液的含量较正常人唾液SIgA的含量明显下降(P<0.05),唾液溶菌酶的含量较正常人明显升高(P<0.05),唾液IgG的含量较正常人无显著性差异(P>0.05),血清免疫球蛋白及补体C3测定结果与正常人无明显变化。结论:复发性口疮与局部免疫有关,其中唾液SIgA与溶菌酶在局部免疫过程中具有非常重要的作用。Objective:To make a further investigation of interrelationship between recurrent aphthae and immunoglobulins.Method:Saliva SIgA, IgG,lysozyme activity and serum immumoglubulin, complement C 3 content were measured in 58 recurrent aphthae patients and non-recurrent aphthae individuals.Result:Saliva SIgA centent of recurrent aphthae patients decreased significantly (P<0.05) compared with that of non- recurrent aphthae individuals while saliva lysozyme increased significantly (P<0.05). No significant differences were detected in saliva IgG, serun immunoglobulin and complement C 3 content (P>0.05).Conclusion:Recurrent aphthae has associations with local immunity. Saliva SIgA and lysozyme play critical roles in local immunity.

关 键 词：唾液 复发性口疮 免疫球蛋白 溶菌酶 

分 类 号：R781.5[医药卫生—口腔医学]