儿童阴茎海绵体神经显微解剖和临床意义  

An anatomical study of the penile cavernous nerve in children

作　　者：万少平[1] 胡礼泉[1] 宋健[2] 田斌群[1] 戴冀斌[2] 郑新民[1] 李世文[3] 

机构地区：[1]武汉大学中南医院泌尿男科研究中心,430071 [2]武汉大学医学院解剖教研室 [3]武汉大学中南医院泌尿男科研究中心',430071

出　　处：《中华小儿外科杂志》2005年第5期246-248,共3页Chinese Journal of Pediatric Surgery

基　　金：国家自然科学基金资助(批准号:30170939)

摘　　要：目的了解儿童阴茎海绵体神经的解剖走向和分布。方法利用手术显微镜,HE染色和神经性一氧化氮合成酶(nNOS)免疫组织化学染色,观察6具完整儿童男尸阴茎海绵体神经的走向和分布。结果阴茎海绵体神经穿过尿生殖膈下筋膜后,走行于阴茎背神经、海绵体动静脉之下,发出1支分支融合入背神经,其余2～3支海绵体神经分支分布于阴茎海绵体脚部。阴茎海绵体神经组织nNOS免疫组织化学染色存在棕黄色nNOS颗粒。结论阴茎海绵体神经于阴茎背神经、海绵体动静脉之下走行,分成分支融合入背神经和分布于阴茎海绵体脚部。Objective To investigate the distribution and location of the penile cavernous nerve in children. Methods Following the cavernous nerve of the neurovascular bundle, detailed anatomical observation and measurement of the penile cavernous nerve were performed on 6 children formalin-preserved cadavers with operative microscope SXP-1B. The genital tissue and penile cavernous nerves from 1 cadaver were explored with HE staining and nitric oxide synthase immunohistochemistry staining. The sections were then observed under microscope. Results The penile cavernous nerve of the neurovascular bundle pierced the inferior genitourinary diaphragm at the posterolateral border of the urethral external sphincter. The distance from the point where the cavernous nerve pierced the inferior genitourinary diaphragm to the urethral was 5.81± 1.37 mm. The diameter of the cavernous nerve is 0.68± 0.22 mm . The cavernous nerve traveled under the penile dorsal nerve and blood vessels after piercing the genitourinary diaphragm. One branch of the cavernous nerve joined the dorsal nerve, and the other 2~3 branches of the cavernous nerve entered into the crural body of the penile corporal body. The positive staining for nitric oxide synthase nerve fibers had been noted in the distal part of the dorsal nerve. Conclusions The penile cavernous nerve of the neurovascular bundle under the genitourinary diaphragm travel under the penile dorsal nerve and blood vessels. One branch of cavernous nerve joins the penile dorsal nerve, and the other 2~3 branches of cavernous nerve enter into the crural body of the penile corporal body.

关 键 词：海绵体神经 临床意义 显微解剖 儿童 免疫组织化学染色 阴茎海绵体 一氧化氮合成酶 阴茎背神经 NNOS 手术显微镜 HE染色 分支分布 神经组织 动静脉 神经性 棕黄色 走行 融合 脚部 

分 类 号：R322[医药卫生—人体解剖和组织胚胎学] R726.92[医药卫生—基础医学]