supported by the National Natural Science Foundation of China(82074036).
Objective:To explore the neuroprotective effects of the Shaoyao Gancao decoction(SGD)against excitatory damage in PC12 cells and the role of the Src-NR2-nNOS pathway mediation by SGD in regulatingγ-aminobutyric acid(...
This review was supported by grants from the National Natural Science Foundation of China(82090042).
In the central nervous system,nitric oxide(NO),a free gas with multitudinous bioactivities,is mainly produced from the oxidation of L-arginine by neuronal nitric oxide synthase(nNOS).In the past 20 years,the studies i...
supported by grants from the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine(ZYYCXTDD-202003);the Science and Technology Program of Sichuan Province,China(2022YFH0006,23RCYJ0059);the São Paulo Research Foundation(FAPESP 2018/07366-4);National Council for Scientific and Technological Development(CNPq,Brasília)(406396/2021-3).
Major depressive disorder(MDD)is one of the most common psychiatric disorders,and~4.7%of the world's population has an onset of depression in any one-year period.It causes constant distress,impairs social function and...
supported by the Natural Science Foundation of Shandong Province(No.ZR2020QC214);the Young Experts of Taishan Scholars(No.tsqn201909130);the Science and Technology Support Plan for Youth Innovation of Colleges and Universities in Shandong Province(No.2019KJF003);the‘First Class Fishery Discipline’Programme in Shandong Province;a special talent programme‘One Thing One Decision(YishiYiyi)’Programme in Shandong Province,China;the Breeding Plan of Shandong Provincial Qingchuang Research Team(2019)。
Neuronal nitric oxide synthase(nNOS)was the producer of nitric oxide(NO)which played important gas messenger molecules in biological process.It also can take effect as immune regulation molecule in organism.Black rock...