儿童化疗后继发肝脾肾霉菌感染的CT检查价值  

CT evaluation in children with hepatosplenic and renal fungal infection after chemotherapy

作　　者：周莺[1] 李玉华[1] 朱铭[1] 江华[2] 邹佳音[2] 

机构地区：[1]上海第二医科大学附属上海新华医院上海儿童医学中心放射科,200127 [2]上海第二医科大学附属上海新华医院上海儿童医学中心小儿血液科,200127

出　　处：《中华放射学杂志》2005年第5期517-519,共3页Chinese Journal of Radiology

摘　　要：目的　了解儿童化疗后继发肝、脾、肾霉菌感染的发生率,提高对该病的CT表现与临床症状的认识。方法　搜集经活检病理证实的106例非霍奇金淋巴瘤(non hodgkin′slymphoma,NHL)或白血病患儿的临床资料,所有病例均行常规胸腹部CT平扫加增强扫描,选出其中8例化疗后继发肝、脾、肾霉菌感染的病例,分析其化疗前后的CT表现。结果　8例中累及肝脏者6例,累及脾脏者6例,累及肾脏者5例。霉菌感染的CT表现为脏器内弥漫性类圆形的低密度影,增强后无强化或呈轻度环形强化。抗霉菌治疗后复查,病灶体积缩小,病灶数量减少或消失。结论　儿童化疗后继发肝、脾、肾霉菌感染发生率较高, CT能很好显示肝、脾、肾霉菌感染,正确及时地诊断肝、脾、肾霉菌感染有助于化疗的正常进行。Objective To understand the incidence of hepatosplenic and/or renal fungal infection after chemotherapy in children, and to recognize the CT findings and clinical manifestation. Methods Clinical materials and CT images of 106 patients with leukemia or lymphoma were reviewed retrospectively. 8 cases of hepatosplenic and/or renal fungal infection after chemotherapy were selected, and CT findings of pre- and post anti-fungal therapy were analyzed. Results Among these 8 cases, the liver was involved in 6, spleen in 6, and kidney in 5. CT findings were multiple round low density lesions. After contrast media administration, there were no or slight enhancement in the lesions. Conclusion The incidence of hepatosplenic and/or renal fungal infection after chemotherapy in children is relatively high. CT can clearly demonstrate the hepatosplenic and/or renal fungal infection. Correct and prompt diagnosis of the hepatosplenic and/or renal fungal infection can help ensure the process of chemotherapy.

关 键 词：霉菌感染 化疗后 继发 CT检查 儿童 lymphoma 非霍奇金淋巴瘤 价值 脾肾 CT表现 腹部CT平扫 白血病患儿 感染发生率 临床症状 病理证实 临床资料 增强扫描 化疗前后 低密度影 体积缩小 弥漫性 治疗后 病例 强化 病灶 

分 类 号：R733[医药卫生—肿瘤]