加味六味地黄汤治疗复发性口腔溃疡疗效分析  

Clinical Study of the Chinese Herbal Medicine Liuwei Dihuang Decoction on Recurrent Oral Ulcer

作　　者：温映萍[1] 莫传伟[2] 郑美华[3] 李银珠[4] 朱美娜[1] 

机构地区：[1]广东省第二中医院口腔科,广东广州510095 [2]广州中医药大学预防医学与卫生统计教研室,广东广州510405 [3]中山大学孙逸仙纪念医院口腔科,广东广州510120 [4]广东省人民医院口腔科,广东广州510080

出　　处：《中医药学刊》2005年第5期949-951,共3页Study Journal of Traditional Chinese Medicine

摘　　要：目的:初步探讨使用中药经方六味地黄汤加减治疗复发性口腔溃疡的疗效。方法:12 0例患者随机分为3组,中药治疗组:内服六味地黄汤加减;西药治疗组:口服左旋咪唑片;观察对照组:口服复合维生素B2 片;观察用药3d、6d时溃疡面积的变化,疼痛缓解程度,对比观察其临床疗效。结果:中药治疗组与西药治疗组间无显著性差异(P >0 .0 5 ) ,但中药比西药更安全,中药治疗组与维生素B2 组、西药治疗组与维生素B2 组间有显著性差异(P <0 .0 5 )。结论:六味地黄汤在复发性口腔溃疡的治疗上有效而安全,值得进一步研究和推广。Objective :To study the clinical effects of the Chinese herbal medicine Liuwei Dihuang Tang on the recurrent oral ulcer(ROU). Methods :120 patients with recurrent oral ulcer were divided into 3 groups randomly.Chinese herbal medicine treatment group :40 examples were taken orally the Chinese herbal medicine Liuwei Dihuang Decoction;Western medicine treatment group:40 examples were taken orally the Levamisole;Observation matched control:40 examples were taken orally compound Vitamin B 2.Observes to 3 days,6 days after using the medicine Ulcerate the partial ache,Ulcer area,exudation,swells,dropsy appearance,contrast observes its clinical curative effect. Results :The Chinese herbal medicine treatment group and the Western medicine treatment group were not different ( P >0.05),but the Chinese herbal medicine is more safe than western medicine,the Chinese herbal medicine treatment group and Western medicine treatment group show significant difference with vitamin B 2 group ( P <0.05). Conclusion :the Chinese herbal medicine Liuwei Dihuang Decoction is an effective and safety prescription,deserve the further research with expand.

关 键 词：复发性口腔溃疡 加味六味地黄汤 疗效分析 六味地黄汤加减 显著性差异 维生素B2片 治疗组 左旋咪唑片 加减治疗 中药经方 初步探讨 溃疡面积 缓解程度 临床疗效 对比观察 西药 对照组 步研究 口服 安全 

分 类 号：R781.5[医药卫生—口腔医学] R733.71[医药卫生—临床医学]