Secreted brevican mRNA is expressed in the adult rat pituitary  

作　　者：DongY, HanX XueY DongB GuoX HuG ZhuC LuY 

机构地区：[1]DepartmentofNeurosurgery,ChangzhengHospital,SecondMilitaryMedicalUniversity,Shanghai2004aa,China

出　　处：《第二军医大学学报》2005年第5期582-582,共1页Academic Journal of Second Military Medical University

摘　　要：Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix (ECM) of the adult rat brain. It has been found only in the central nervous system (CNS). In this study, we found that secreted brevican transcript was detectable in the pituitary of both male and female adult rats by reverse transeriptase-polymerase chain reaction (RT-PCR)amplification. In posterior lobe of pituitary, pituicytes were heavily labelled. In anterior and intermediate lobes of pituitary,signals for brevican transcripts were observed in cells of various sizes. These data demonstrated that secreted brevican mRNA is expressed in the adult rat pituitary and brevican might not be a CNS-specific ECM。

关 键 词：MRNA 分泌机制 成年 小鼠 动物实验 垂体 

分 类 号：R742[医药卫生—神经病学与精神病学]