正常青年人数字计算与脑血流速度的相关性研究  

Study of the correlation between digit and arithmetic activities and cerebral blood flow velocity changes in youth people

作　　者：王文富[1] 刘诗翔[1] 汪洪[1] 李筱媛[2] 梁燕[1] 王琳[1] 刘枢晓[1] 

机构地区：[1]成都军区昆明总医院神经内科,昆明650032 [2]云南省第一人民医院风湿免疫科

出　　处：《中国行为医学科学》2005年第4期315-317,共3页Chinese Journal of Behavioral Medical Science

摘　　要：目的探讨数字默读和数字计算对脑血流速度(CerebralbloodflowvelocityCBFV)的影响及性别和任务完成质量对CBFV变化的影响。方法在完成认知任务时及其先前的休息期,对45个正常的志愿者(右利手)用经颅超声多普勒(TCD)监测其双侧大脑中动脉CBFV的变化。结果完成认知任务时与休息时相比,数字默读的相对变化值左侧为8. 6±4. 6,右侧为7. 4±4. 7;数字计算任务相对变化值左侧为14. 5±4. 6,右侧为8. 8±4. 6;两个任务均诱导出双侧大脑中动脉CBFV的显著增加(P<0. 001)。数字默读的偏侧指数(LI)为7. 4±19. 2(P<0. 05);数字计算的LI为26. 3±24. 7(P<0. 01),均呈现出显著的左侧半球偏侧化。性别对CBFV偏侧化不产生显著影响,但计算任务诱导的CBFV的增长在两性间有显著的差异(P<0. 05);表现质量(得分)对CBFV的变化不产生显著的影响。结论数字默读、数字计算可诱导CBFV的左侧偏侧化。ObjectiveTo investigate the effect of cerebral blood flow velocity(CBFV) induced by digit and arithmetic cognitive tasks and to determine the influence of gender, quality of the performance on the relative CBFV changes. MethodsSimultaneous bilateral transcranial ultrasonography Doppler (TCD) monitoring of CBFV in the middle cerebral arteries (MCAs) was performed in right-handed 45 normal volunteers during digit and arithmetic tasks and their preceding rest periods. ResultsCompared with their preceding rest periods,the relative CBFV changes of digit cognitive tasks in left was 8.6±4.6 and in right was 7.4±4.7; the relative CBFV changes of arithmetic cognitive tasks in left was 14.5±4.6 and in right was 8.8±4.6.Two tasks induced a significant bilateral CBFV increase in the MCAs (P<0.001) and showed a significant left-hemisphere CBFV acceleration(The laterality index of digit cognitive tasks was 7.4±19.2 and arithmetic cognitive tasks was 26.3±24.7). Gender had no influence on laterality, but higher relative CBFV changes were observed in the male group when arithmetic cognitive task was performed. Performance quality did not reveal significant effects on CBFV change. ConclusionDigit and arithmetic cognitive tasks can induce a significant left-hemisphere CBFV acceleration.

关 键 词：脑血流速度 相关性研究 正常青年人 数字 经颅超声多普勒 大脑中动脉 相对变化 计算任务 blood 默读 左侧 右利手 志愿者 侧化 质量 性别 休息 认知 双侧 右侧 

分 类 号：R33[医药卫生—人体生理学]