Tourette 综合征的共病临床研究  

A Preliminary Study of Comorbidities Associated with Tourette Syndrome

作　　者：杨建红[1] 张世吉[1] 佘永军[1] 郑毅[1] 崔永华[1] 梁月竹[1] 范萌[1] 

机构地区：[1]首都医科大学附属北京安定医院,北京100088

出　　处：《中国心理卫生杂志》2005年第6期413-415,共3页Chinese Mental Health Journal

摘　　要：目的:了解Tourette 综合征共病的种类、发生率及相关因素。方法:以CCMD-3诊断标准为依据, 分别采用耶鲁综合抽动严重程度量表(YGTSS)、Achenbach 儿童行为量表(CBCL)、莱顿(Leyton)强迫量表、康纳(Conners)儿童行为问卷和家庭情况调查表,对125例Tourette 综合征逐一进行评定。结果:Tourette 综合征与注意缺陷多动障碍共病率为41.6%,与强迫症的共病率为25.6%,与焦虑障碍的共病率为8.0%,与抑郁障碍的共病率为4.8%,与品行障碍的共病率为8.0%,与自伤的共病率为3.2%,与睡眠障碍的共病率为2.4%。结论: Tourette 综合征的共病种类多,患病率高,影响TS 的治疗及预后。共病通常是TS 儿童功能损害的来源,并增加疾病的复杂性和严重性,应该引起高度重视。Objective:To explore the category,prevalence and related factors of comorbidities associated with Tourette syndrome.Methods:125 patients with TS according to CCMD-3(Chinese Classification of Mental Disorders,3rd edition)were assessed with a self-designed family circumstance questionnaire,YGTSS,CBCL,Leyton obsessive-compulsive scale,and Conner's Child Behavior Checklist.Results:Of 125 TS patients,the comorbidities included attention deficit and hyperactivity disorder(ADHD,41.6%),obsessive-compulsive disorder(OCD,25.6%), anxiety disorders(8.0%),depressive disorders(4.8%),conduct disorders(8.0%),self-injurious behavior(3.2%),and sleep disorder(2.4%).Conclusion:There are many kinds of comorbid disorders at high prevalence in TS patients. These comorbidities adversely influence the therapy and prognosis of TS and are taken as the possible reasons for social function deficit.

关 键 词：Tourette综合征 ACHENBACH儿童行为量表 临床研究 注意缺陷多动障碍 家庭情况调查表 CCMD-3 严重程度量表 儿童行为问卷 共病率 诊断标准 强迫量表 焦虑障碍 抑郁障碍 品行障碍 睡眠障碍 功能损害 发生率 强迫症 病种类 

分 类 号：R749.94[医药卫生—神经病学与精神病学] R179[医药卫生—临床医学]