急性眼压改变对兔眼球后动脉血流动力学的影响  

A study of hemodynamic changes in the arteries of rabbit′s eye caused by acute high intraocular pressure

作　　者：李恒岩[1] 冷瀛[2] 张铁山[3] 胡颖[3] 李薇[1] 

机构地区：[1]吉林市中心医院电诊科,132000 [2]北华大学附属医院眼科 [3]北华大学附属医院超声诊断研究室

出　　处：《中华眼科杂志》2005年第5期449-453,共5页Chinese Journal of Ophthalmology

摘　　要：目的　应用超声彩色多普勒诊断仪对短期内不同眼压条件下兔眼球后动脉的血流动力学参数进行对比研究。为临床上选择降眼压、改善眼球后动脉血流药物的筛选提供理论依据。方法　进行兔左眼球后动脉的自身对照研究:制作兔眼的高眼压模型。测量正常眼压、高眼压及高眼压后人为再恢复至正常眼压这三种条件下眼球后动脉血流动力学参数。结果　兔眼动脉、视网膜中央动脉、睫状动脉主干及睫状后短动脉均为低阻力血管,当眼压迅速增高时,以上各动脉的血流阻力指数增高,流速降低,当使眼压短期内恢复正常后,大部分血流参数不能恢复至正常水平。结论　眼压短期内的变化影响眼球后动脉血流动力学的变化。彩色多普勒超声测量技术是对这种改变进行监测的较好方法。Objective Using the color Doppler flow imaging (CDFI) to measure and to study the hemodynamic changes of rabbit′s retrobulbar artery caused by changes of intraocular pressure (IOP). To provide information for screening of drugs that improves the blood circulation and decrease the IOP. Methods This is a self-contrast research performed at the left eye: high IOP was induced, then the hemodynamic changes of rabbit′s retrobulbar artery at different IOP stages were observed. Results Rabbit′s ophthalmic artery (OA), ciliary artery (CA), short posterior ciliary artery (SPCA), central retinal artery (CRA) are low resistant artery. When the IOP raised rapidly, the velocity of blood flow became slower and resistance force index became higher. The hemodynamic changes could not return to normal even after the IOP decreased to the normal level. Conclusion A short-term high IOP can influence the hemodynamic pattern of retro-bulbar arteries. Color Doppler flow imaging is a valuable method for monitoring these changes.

关 键 词：动脉血流动力学 眼球后 眼压改变 血流动力学参数 彩色多普勒诊断仪 视网膜中央动脉 彩色多普勒超声 急性 自身对照研究 睫状后短动脉 血流阻力指数 正常眼压 高眼压模型 后动脉 对比研究 阻力血管 动脉主干 血流参数 测量技术 

分 类 号：R775[医药卫生—眼科]