不同浓度氟保护漆抑制人牙釉质脱矿能力的体外研究  

A study on inhibitory effect of different concentrations of fluor protectors on demineralization of human enamal

作　　者：林居红[1] 王金华[1] 杨刚[1] 马文竹[1] 贺鸿星[1] 庞书 

机构地区：[1]重庆医科大学口腔医院口腔预防医学教研室,重庆400015 [2]重庆市中小学卫生保健所,重庆400020

出　　处：《重庆医科大学学报》2005年第3期429-431,434,共4页Journal of Chongqing Medical University

基　　金：重庆市卫生局科研基金资助(03-2-013)

摘　　要：目的:观察和比较两种浓度氟保护漆在体外抑制人牙釉质脱矿的能力。方法:将预备好的40个无龋的牙釉质块随机分为4组,每组10个标本,5个用作实验,5个备用;0.5%氟保护漆组、0.1%氟保护漆组为实验组,0.02%氟化钠为阳性对照组,去离子水为空白对照组,经过人工酸蚀48h后,分别采用原子吸收分光光度计和紫外分光光度计测量酸蚀液中的钙、磷溶出量。结果:实验组抑制钙、磷溶出效果明显好于对照组。实验组和对照组之间有高度的显著性差异(P<0.0001);实验组之间没有显著性差异(P>0.05);对照组之间有显著性差异(P<0.05)。结论:两种浓度的氟保护漆都能够有效的抑制离体人牙釉质的脱矿反应;两者之间抑制牙釉质脱矿能力没有显著性差异。Objective:To observe and compare the inhibitory effect of two concentrations of fluor protectors on demineralization of human enamel in vitro.Methods:40non-carious human enamels were randomly divided into four groups with 10 samples in each group,of which 5 samples were used for experiment,5 samples were used as spare ones.0.5% fluor protector and 0.1% fluor protector were applied to the experiment groups,while 0.02% sodium fluoride and deionizer water were applied to the control groups.Then the specimens had been dematerialized for 48h,the amounts of phosphorus and calcium dissolved in the acid solution were determined by atomic absorption spectrophotometer and ultraviolet spectrophotometer respectively.Results:The experiment groups were better than the comtrast groups at preventing demineralization,and there was significant difference between experiment groups and contrast groups(P<0.0001);There was no significant difference between 0.5% fluor protector group and 0.1% fluor protector group (P>0.05);but there was significant difference between 0.02% sodium fluoride group and vavuity group (P<0.05).Conclusion:Both two different concentrations of fluor protectors are effective in inhibiting demineralization of human enamel in vitro.There is no significant difference between two groups in their inhibitory effects.

关 键 词：氟保护漆 抑制 牙釉质 脱矿 

分 类 号：R780.1[医药卫生—口腔医学]