机构地区:[1]广州医学院临床肿瘤研究中心中西医结合科,广东省广州市510095 [2]肇庆市第一人民医院,广东省肇庆市526020
出 处:《中国临床康复》2005年第18期251-253,共3页Chinese Journal of Clinical Rehabilitation
摘 要:背景:传统中药疗法和导引运动可以改善癌症生存期患者的不适感觉,如减少疲劳感,提高对化学药物治疗的耐受性等作用已被公认。但对其效果的量化评定标准选择应该是科学的。目的:应用生活质量量表评估,扶正中药配合导引运动对肺癌患者生存状态的影响。设计:非随机化同期对照观察。单位:广州医学院临床肿瘤研究中心中西医结合科;肇庆市第一人民医院。对象:选择1997-10/2001-03广州医学院临床肿瘤研究中心中西医结合科收治的肺癌住院患者60例,男41例,女19例,其中治疗组30例,对照组30例,均为自愿参加。方法:治疗组化疗同时给以扶正中药并配合导引运动疗法,对照组给以单纯化疗。两组采用相同的化疗方案。由同一熟悉“生存质量评价表”的医师在每疗程前后评价两组患者的生活质量,同时观察两组病例化疗疗程完成情况。生活质量评价采用“中国人肺癌生存质量评价表”进行评价,内容包括肺癌引起的生理状况、社会/家庭状况、对医生及疾病态度的关系、情感状况、功能状况共5个因子。两组分别完成1,2疗程病例统计分析。主要观察指标:①两组患者治疗前后生活质量评分比较。②两组化疗疗程完成情况。结果:按意向处理分析,60例患者均完成实验。两组患者治疗前后生活质量评分比较:①治疗组治疗后生理状况评分明显低于治疗前[(14.1±3.2),(31.7±2.9)分,P<0.01]和对照组[(20.0±3.5)分,P<0.05]。②社会/家庭状况评分明显高于治疗前[(25.2±3.1),(12.2±2.3)分,P<0.01]也高于对照组[(19.1±2.2)分,P<0.05]。③对医生及疾病态度的关系评分明显高于治疗前[(37.4±5.2),(24.2±3.5)分,P<0.01]也高于对照组[(29.1±3.4)分,P<0.05]。④情感状况评分明显高于治疗前(43.8±5.6),[(28.5±4.7)分,P<0.01]也高于对照组[(34.5±3.3)分,P<0.05]。⑤功能状况评分明显高于治疗前[(26.3±2.3),(17.3±3.3)分,P<0.0BACKGROUND:It has been recognized that the traditional herbal treatment and d aoyin exercises(physical and breathing exercise)can relieve the symptoms such as tiredness of cancer patients and strengthen the tolerance to chemical drugs.But the criterion of quantitative evaluation for the effect should be scientific. OBJECTIVE:To evaluate the influence of Chinese herb for strengthening the bod y resistance and daoyin exercises on the survival state of lung cancer patients with the evaluation scale of life quality. DESIGN:Non- randomized and concurrent controlled trial. SETTING:Department of Integrated Traditional Chinese and Western Medicine,Cli nical Cancer Research Center,Guangzhou Medical College;Zhaoqing First People's H ospital. PARTICIPANTS:Totally 60 inpatients of the Department of Integrated Traditiona l Chinese and Western Medicine of Clinical Cancer Research Center of Guangzhou M edical College were enrolled from October 1997 to March 2001 in the study.All of them were volunteers.There were 41 males and 19 females,30 patients in the trea tment group and 30 in the control group. METHODS:The treatment group was given chemical therapy,at the same time,the h erbal treatment and daoyin exercises.The control group was given chemical therap y only.The same chemical therapy was applied to both groups.The appointed doctor familiar with the evaluation table of quality of life was responsible for evalu ating the quality of life of the patients in the two groups before and after tre atment and the observation of their accomplishment of chemical therapy.The evalu ation table of quality of life of Chinese lung cancer patients was used in the e valuation.The table included 5 factors:the physiological state caused by lung ca ncer,social/family state,relation of altitude towards doctor and disease,emotion al state,and functional state.The statistical analysis was done to see the accom plishment of chemical therapy of two groups. MAIN OUTCOME MEASURES:① The score comparison of quality of life before and a fter treatment
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