复方五倍子煎剂对变形链球菌抑菌作用的实验研究  

The experiment study of Chinese herbs (GRE) on anti-streptoccus mutans effect

作　　者：熊炎斌[1] 刘持平[1] 黄岚[1] 

机构地区：[1]咸宁学院口腔医学系,湖北咸宁437000

出　　处：《临床口腔医学杂志》2005年第6期331-333,共3页Journal of Clinical Stomatology

基　　金：湖北省教育厅重点资助项目 (2 0 0 0B440 1 0 )

摘　　要：目的:观察复方五倍子制剂对变形链球菌的抑制作用。方法:将五倍子、大黄、甘草等10味中草药制成煎剂(GER) ,测量其不同浓度对变形链球菌生长、产酸、粘附等作用的抑制效果。结果:当GRE浓度为10 0 %时(最终浓度2 0 %W /V) ,细菌生长量仅为对照组的3 5 .6% ;粘附率下降12 .7% ;pH值升高1.5 4。药物浓度为5 0 %时(最终浓度10 %W /V) ,与对照组比较,细菌生长和粘附作用分别下降43 .8%和10 .6% ,pH值升高1.18。结论:GRE对变形链球菌有一定的抑制作用。Objective:To study galla- rhubarb elixation(GRE) inhibiting effectiveness on Streptoccus Mutans (S .Mutans) in vitro .Method:The experiment was carried out by making GRE. Then adding four kinds concentration GRE to the cultures respectively to determine the inhibition effectiveness to the growth. acid production and Adherence of S. Mutans.Result:In contrast with the control group, when concentration of GRE is 100% (w/v), the growth rate of S.Mutans reduces 64.4%; adherence rate reduces12.7%; PH rises 1.54. when concentration of GRE is 50% (w/v), the growth rate of S.Mutans reduces43.8%; adherence rate reduces10.6 %; PH rises 1.18.Conclusion:The galla-rhubarb elixation has some anti-Streptoccus Mutans effect.

关 键 词：复方五倍子煎剂 变形链球菌 中药 

分 类 号：R780.2[医药卫生—口腔医学]