Comparing Gross Tumor Volume of Delineation between CT and MRI for Nasopharyngeal Carcinoma  

CT和MRI确定鼻咽癌原发肿瘤靶区对比研究(英文)

作　　者：唐曦 胡国清[1] 邱红 崔巍 

机构地区：[1]武汉华中科技大学同济医学院附属同济医院肿瘤中心,430030

出　　处：《The Chinese-German Journal of Clinical Oncology》2005年第3期141-145,187,共6页中德临床肿瘤学杂志（英文版）

基　　金：This work was supported by a grant from the National Natural Science Foundation of China (No. 30470525).

摘　　要：Objective: To study the accuracy between CT and MRI in delineating gross tumor volume (GTV) of nasopharyngeal carcinoma (NPC) in making radiotherapy plan. Methods: The clinical data of 39 cases pathologically proven as nasopharyngeal carcinoma selected from April 2003 to September 2004 were retrospectively analyzed. All were subjected to CT and MR examination one week before treatment. CT scanning was performed with GE Light speed 16, and axial scan was parallel to the OM line routinely from soft palate to the suprasellar cistern. MR scanning was performed by GE Signa super-conducting magnetic resonance imaging system (1.5 Tesla). The standard quadrature head coil was used. Routine axial, sagittal and coronal image with SE sequence were obtained, and FLAIR was used in 10 of 21 cases. Scanned field ranged from the soft palate to the suprasellar cistern. Part of all cases underwent enhanced scanned with Ultravist in CT group or/and GD-DTPA in MR group. All data were analyzed by using the paired-samples t test. Results: The media primary tumor volume (cm3) in CT group and MR group was 32.49±19.91, 29.06±18.75, respectively, and the difference between the two groups were significant (t=5.268, P=0.000). There was significant difference between the two groups in early stage (T1+T2) and advanced stage (T3+T4) by Fuzhou Staging System (t=5.677, P=0.000; t=3.310, P=0.005, respectively). There was significant difference in stage T1, T2, T3 (P=0.005, P=0.001, P=0.004, respectively), and not in stage T4 (P=0.146) between the two groups. Conclusion: MR was more accurate than CT in delineating GTV of NPC, so, is more valuable in making radiotherapy plan.

关 键 词：nasopharyngeal carcinoma tomography  X-ray computed magnetic resonance imaging gross tumor volume 

分 类 号：R739.63[医药卫生—肿瘤]