恶性肿瘤病人血清FDP检测及临床意义的探讨  

The Study of FDP Blood Content in Patients with Malignancy

作　　者：朱建思[1] 周建国[1] 董琳 

机构地区：[1]衡阳医学院肿瘤研所,衡阳市421001

出　　处：《中国肿瘤临床》1994年第7期528-530,共3页Chinese Journal of Clinical Oncology

摘　　要：应用单克隆抗体检测恶性肿瘤病人血中FDP,结果显示,肿瘤病人血液中FDP含量明显高于正常人(P<0.01).在消化、呼吸系统等多种恶性肿瘤病人中,FDP值以高恶性的肝细胞癌含量最高.临床观察结果显示肿瘤增长速度快以及发生了转移的患者比病情稳定的患者FDP含量普遍增高(P<0.01).本文结果提示FDP检测还可能对肿瘤的转移及预后判断有一定作用.The blood FDP (fibrin degradation product) content in patients with malignant tumors were determined with McAb. The result showed that serum FDP content in cancer patients was much higher than that in normal individuals and was highest in hepatocellular carcinoma patients. Clinical observation also indicated that serum FDP content in patients with rapidly growing and metastasizing tumor was generally higher than that in patients with slowly progressing disease. The result also suggested that FDP determination could play a significant role in assessing the progress of cancers.

关 键 词：肿瘤 FDP 单克隆抗体 癌 

分 类 号：R730.231.3[医药卫生—肿瘤]