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作 者:张文智[1] 安会波[1] 陈秀鉴[2] 魏守礼[2] 黄志远[3]
机构地区:[1]河北省儿童医院,石家庄市050031 [2]河北医学院 [3]中国人民解放军二六○医院
出 处:《中国肿瘤临床》1994年第7期501-504,共4页Chinese Journal of Clinical Oncology
摘 要:65例非何杰金氏淋巴瘤进行了DNA含量、S期细胞百分率(%S)、Ag-NORs和形态学观察多项参数的综合分析,结果表明DNA含量、%S和Ag-NORs的值明显高于正常淋巴对照(P<0.01)。NHL非整倍体占69%,高于文献报告的40%-50%。二倍体肿瘤15例(23%)。各项参数值在高度恶性和中度恶性组明显高于低度恶性组(P<0.01)。%S和Ag-NORs呈正相关(直线相关回归分析r=0.Sixty five cases of non-Hodgkin' s lymphoma (NHL) were studied with respect to the DNA content,the percentage of S phase cells(%S) ,Ag-NORs and morphologic observation. Analytic results demonstrated that DNA content,%S and Ag-NORs were distinctly higher than the control group(P<0. 01). Aneuploid of NHL was 69%(45/65), higher than that in the literature (40%-50%). All parameters were higher in the high and intermediate grade malignancy than in the lower grade(P<0. 01). %S and Ag-NORs were positively related to and reflected the cellular activity (r = 0. 307 P<0. 05).Multiparametric analysis is necessary in the diagnosis of doubtful cases. The diagnosis can be established if two of the parameters are elevated. Pathologic morphology is still of importance in the NHL diagnosis.
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