针药结合治疗高血压及对血浆神经肽Y的影响  

Effect of acupuncture combined with medicine on neuropeptide Y in the patient of hypertension

作　　者：张艳玲[1] 李创鹏[1] 彭敏[1] 杨慧珊[1] 

机构地区：[1]广东省中医院珠海医院,珠海519015

出　　处：《中国针灸》2005年第3期155-157,共3页Chinese Acupuncture & Moxibustion

基　　金：广东省中医药局科研基金资助课题:102154

摘　　要：目的:寻找能提高治疗高血压病临床疗效的方法,并探讨其作用机理。方法:将75例患者按入院先后顺序随机分为2组,针刺加药物组(治疗组)45例及药物组(对照组)30例。观察治疗前后血压、血浆神经肽Y(NPY)的变化情况。结果:治疗组、对照组治疗后均能明显降低血压及NPY含量(P<0.01),且治疗组的效果优于对照组(P<0.05)。结论:针药结合治疗高血压有协同作用,能提高疗效。其作用机理可能是通过降低NPY实现的。Objective To search for a method for increasing therapeutic effect on hypertension and study on the mechanism. Methods Seventy-five cases were randomly divided into the treatment group (n = 45) treated by acupuncture plus medicine, and the control group (n = 30) treated by medicine. Their blood pressure and plasma neuropeptide Y (NPY) before and after treatment were investigated. Results Blood pressure and NPY content in both the two groups decreased significantly (P<0. 01), and the treatment group in decreasing blood pressure and NPY content was superior to the control group (P<0. 05). Conclusion Acupuncture and medicine have cooperation in treatment of hypertension, which is performed possibly through decreasing NPY.

关 键 词：针药结合治疗 血浆神经肽Y 作用机理 对照组 治疗组 临床疗效 高血压病 先后顺序 治疗前后 变化情况 降低血压 协同作用 NPY 治疗后 药物 

分 类 号：R277.751.2[医药卫生—中医学] R743.33