胃动脉内化疗灌注与合用栓塞的对照实验研究  

Experimential Studies of Gastric Arterial Chemotherapeutic Infusion and Chemoembolization

作　　者：李茂全[1] 林贵[1] 胡锡琪[1] 

机构地区：[1]上海医科大学中山医院放射科,上海医科大学病理学教研室

出　　处：《中华放射学杂志》1994年第3期153-155,共3页Chinese Journal of Radiology

摘　　要：本资料报告１６例正常新西兰大白兔采用胃动脉内化疗灌注与合用栓塞的两种实验结果。研究表明两种方法均对胃组织有一定损伤，以栓塞组为重。损伤主要局限于粘膜和粘膜下层，肌层及浆膜层正常；表现为水肿和局灶性细胞脱落、糜烂等。术后３０～４５天均表现正常。两种方法无明显肝功能损害。结果表明：胃动脉内化疗栓塞，尤其碘化油乳化物栓塞是可行的，为晚期胃癌的治疗提供了一种新方法。The experimental results of 16 New Zealand white rabbits were reported,of which,7 were managed by gastric arterial infusion(GAI)and 7 by chemoembolization(GAE)The results showed that both GAI and GAE led to injury of gastric tissue,mainly the mucosa and submucosa.The chief pathological changes with GAI were sight edema and inflammation,and with GAE,edmia,actue inflammation and focal necrosis.The muscular and serious layers were intact in both groups.Recovery of the damaged gastric membrane occurred within 30-45 days after treatment.Transient changes of liv-er functions and blood routine examination were observed The results demonstrated that GAE is clinically feasible in managing advanced gastric cancer,with no obvious complication.

关 键 词：动物 胃肿瘤 癌 药物疗法 栓塞疗法 

分 类 号：R735.205[医药卫生—肿瘤]