大鼠肝癌肝动脉碘油柱塞后的门脉血供  

Portal Blood Supply of Liver Tumor after Hepatic Arterial Embolization in Rat

作　　者：董永华[1] 林贵[1] 

机构地区：[1]上海医科大学中山医院放射科

出　　处：《中华放射学杂志》1994年第9期582-584,共3页Chinese Journal of Radiology

摘　　要：采用软Ｘ线摄影技术和硅酮灌注技术，对二乙基亚硝胺诱发的大鼠肝癌模型作碘油肝动脉栓塞后的肿瘤门脉血供进行了研究。结果显示：碘油肝动脉栓塞后，较大肿瘤结节（＞５ｍｍ）的周边部分可见门脉血供存在，而较小肿瘤结节内（＜５ｍｍ），其肿瘤血供呈现部分或完全来自门脉。作者认为，碘油肝动脉栓塞不可能产生完全性的肿瘤双重血供的栓塞；门脉血供的存在可能是碘油肝动脉栓塞后部分肿瘤细胞残存的一个重要原因。因此，在碘油肝动脉栓塞后有必要进行经门静脉途径的介入治疗。Using low-kilovotage radiography and Microfil perfusion technique the authors investigated the distribution of lipiodol and portal blood supply of tumor after lipiodol hepatic arterial em-bolization (HAE)in rats with N-nitrosediethylamine-induced liver cancer.The results showed that after lipidol HAE, there was portal blood supply for the peripheral part of the larger tumor noduees(>5mm ); whereas in tumor nodules less than 5mm in diameter,part of total blcod supply was provided by the portal vein with little of no lipiodol accumulation. The authors believed that complete dual emboliza-tion of tumor blood supply could not be achieved by lipiodol HAE,and portal blood supply to the tumor might be the major cause of survival of tumor cells after lipiodol HAE.It is reasonable to suggest that interventional therapy via portal vein following lipiodal HAE is necessary in the treatment of hepatic can-cer.

关 键 词：肝肿瘤 癌 碘油 栓塞疗法 细胞瘤 

分 类 号：R735.7[医药卫生—肿瘤]