惊恐障碍与心绞痛患者血清一氧化氮水平对照研究  

Comparative study on serum nitric oxide level between panic disorder and angina pectoris

作　　者：王旭梅[1] 夏静[1] 李艳辉[1] 金魁和[1] 

机构地区：[1]中国医科大学第二临床医院,沈阳110004

出　　处：《临床精神医学杂志》2005年第3期132-134,共3页Journal of Clinical Psychiatry

基　　金：辽宁省教育厅2000年度高等学校科学研究项目(项目号20122181)

摘　　要：目的:探讨惊恐障碍与心绞痛之间的关系。方法:检测并比较17例惊恐障碍(惊恐障碍组)与27例心绞痛(心绞痛组)及39名健康者(对照组)血清一氧化氮(NO)和一氧化氮合酶(NOS)。结果:两患者组血清NO水平均显著低于对照组,惊恐障碍组与心绞痛组比较血清NO水平无显著差异;惊恐障碍组血清NOS水平与对照组比较无显著差异,心绞痛组血清NOS水平显著低于对照组,两患者组血清NOS水平无显著差异。结论:惊恐障碍与心绞痛症状相似可能与NO的下降有关。惊恐障碍成为心绞痛的危险因素由NO下降得到解释。Objective:To study the relationship between angina pectoris and panic disorder.Method:Serum nitric oxide (NO) and nitric oxide synthase(NOS) level were measured in 17 patients with panic disorder (PD) and 27 patients with angina pectoris and 39 normal controls.Results:Serum NO level in both patients groups were significantly lower than that in the controls.There was no significant difference in serum NOS level between PD group and control group,but NOS level were significantly lower in angina pectoris group than in control group. No significant differences were found in the serum NOS and NO levels between angina pectoris group and PD group.[WTHZ]Conclusion:The similar symptoms between angina pectoris and PD might be associated with the decreasing of NO, which also can be used to explain that PD is one of the risk factors of angina.

关 键 词：惊恐障碍 心绞痛 一氧化氮 一氧化氮合酶 

分 类 号：R749.7[医药卫生—神经病学与精神病学]