急性缺血性脑卒中的急诊溶栓治疗  

Emergent Thrombolytic Therapy of Acute Ischemic Stroke

作　　者：蒋兆贯[1] 陆进[1] 徐淦泉[1] 夏晓[1] 陈宏伟[1] 余准[1] 崔志敏[1] 童耀英[1] 

机构地区：[1]江苏无锡市第一人民医院,214002

出　　处：《医学影像学杂志》1998年第2期81-83,共3页Journal of Medical Imaging

摘　　要：目的：为了评价超选择性动脉内溶栓治疗急性缺血性脑卒中的适应证、疗效及安全性。材料和方法：本组20例病人接受了超选择性动脉内灌注尿激酶的治疗方法，尿激酶用量20万单位一100万单位，溶栓治疗时间45至200分钟。临床疗效评价于溶栓治疗后一个月进行。结果：6例血管完全再通，12例部分再通；2例本通，再通率90％，临床治疗有效率80％，显效率60％。20例中有2例术后对侧出现脑梗塞且临床症状加重，20例中无一例并发颅内出血。结论：我们认为急诊溶栓治疗是一种安全有效的治疗方法。Purpose: To evaluate the indication, the efficacy and the safety of super selective intraarterialthrombolytic therapy of acute ischemic stroke. Materials and methods:There were 20 cases of acute ischemic strokewhich were treated with intra - arterial urokinase (uk ) infusion by superselective catheterizaation, 200000～1000000 of urokinase was used,and the duration of thromblysis was 45-200 minutes and the clinical efficacy wasevaluated after one month. Results:Complete patency was seen in 6 cases,part patency was seen in 12 cases,theother 2 cases were still occlusive. the recanalization rate was 90%,the clinical effective rate was 80%,the more ef-fective rate was 6O%. Two of twenty cases had heavier clinical appearance after operation and had contralateral in-farction. None of 20 cases had complicated hemorrhage. Conclusion:We concluded that emergent thrombolytic ther-apy of acute lschehac stroke was a safe and effective method.

关 键 词：急性缺血性脑卒中 急诊溶栓 适应证 尿激酶 介入疗法 动脉内溶栓 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R815[医药卫生—临床医学]