爱肌松的药效学及其对循环功能的影响  

The pharmacodynamics of alcuronium and atracurium and their erfects on circulatory function.

作　　者：杭燕南[1] 孙大金[1] 王祥瑞[1] 皋源 龚国庆 

机构地区：[1]上海第二医科大学附属经济医院麻醉科,邮政编码200001

出　　处：《中华麻醉学杂志》1994年第4期272-274,共3页Chinese Journal of Anesthesiology

摘　　要：对６６例心脏病手术和非心脏病手术患者，比较爱肌松和阿曲可林的药效学及其对循环功能的影响．结果表明：（１）在心脏手术中，两药起效时间相近；（２）近５０％的爱肌松组病例需用新斯的明拮抗；（３）两药对循环功能无明显影响。因此，爱肌松适用于心脏和非心脏病手术患者的麻醉诱导和维持。The pharmacodynamics and its circulatory effects of alcuronium and atracurium were investigated in cardiac and noncardiac surgical patients.The results demonstrated that:l Compared with atracurium group,the duration of action of alcuronium is longer in cardiac patients than that of non-cardiac patients, but there is no difference in the onset of action between these two groups; 2. Half of the patients which received alcuronium need reversal with neostigminel 3. The effects on the circulation of these two drugs were nor remarkable;Therefore,alcuronium is also suitable for cardiac and non-cardiac surgical patients

关 键 词：爱肌松 阿曲可林 循环 药理学 

分 类 号：R971.2[医药卫生—药品]