我国类鼻疽流行病学调查  

EpidemiolOgy of Melioidosis in China

作　　者：李俐[1] 陆振豸[1] 韩藕儿 张我东 赵忠利[1] 

机构地区：[1]军事医学科学院微生物流行病研究所,广州军区军事医学研究所

出　　处：《中华流行病学杂志》1994年第5期292-295,共4页Chinese Journal of Epidemiology

摘　　要：笔者于１９７５～１９８９年对我国南方琼、粤、桂、湘四省区不同纬度的１３个县市进行类鼻疽菌分离，从１０个县市的水样品和人、畜病理标本中共获得７３株类鼻疽假单胞菌。血清学调查发现抗体阳性率与病菌的分布呈相关关系。井证实疫源地分布于粤、桂、琼的南亚热带和边缘热带地区。疫区人群抗体阳性率为３．８％～１５．２％，马为９．１％～１８．４％，牛为６．６％～３３．０％，感染猪群阳性率高达３５．０％，屠宰猪标本分离率为１３％。类鼻疽的危害调查表明，马、骡感染后会干扰鼻疽检疫。病菌污染肉品，危害公共卫生。在１９８９年９至１０月份的一次临床病例调查中，在湛江和海南三亚发现３例患者，２例因败血症死亡，１例为慢性下肢溃疡，可能还有显性感染患者被漏诊或误诊．From 1975 to 1989,a total of 73 strains ofP.pseudomallei was isolated from the watersamples and the pathological samples of humanand domestic animals in 13 counties and citieslocated different latitute from four provincesQiong,Yue,Gui and Xiang in China.Serologlcalinvestigation demonstrated that the geographicaldistribution of the organism had a significantcorrelation with the positive rate of antibodiesagainst P.pseudomallei and the native foci ofthe organisms distributed over the southern sub-tropical zone and the edge of tropical zone inQiong,Yue and Gui.In endemic areas,the posi-tive rates of antibodies against P.pseudomal-lei in human-beings,horses,oxen and pigs are3.8%～15.2%,9.1%～18.4%,6.6%～33.0%and 35%respectively.The investigation results showedthe horses and mules infected by the organismwould interfer with guarantine of the animals,mean while,the meat contaminated by the bac-terium would endanger the public health.In Se-pt·and Oct·of 1989,three cases in Zhanjiang andSanya of Hainan were reported, two cases diedof acute melioidosis with septicemia,anothercase was the chronic leg ulcers.So,it was pre-dicated that there could have some cases ofmelioidosis which were misdiagnosed or missedout.

关 键 词：类鼻疽 类鼻疽菌 疫源地 血清学 

分 类 号：R754.301[医药卫生—皮肤病学与性病学]