选择性肝动脉化疗药物灌注及栓塞治疗肝转移癌  

Selective hepatic arterial infusio n chemotherapy and embolization in t he treatment of liver metastases

作　　者：温树伟[1] 党之俊[1] 张晓前[1] 翟守仁[1] 

机构地区：[1]山西省肿瘤医院,太原市030013

出　　处：《实用医学影像杂志》2001年第3期162-163,167,共3页Journal of Practical Medical Imaging

摘　　要：目的探讨选择性肝动脉化疗药物灌注及栓塞治疗肝转移癌的价值。材料与方法对122例失去手术机会的肝转移癌患者,采用经股动脉穿刺,选择性肝动脉插管灌注化疗药物ADM,MMC,CDDP,5-FU,并用ADM及碘化油乳化后检塞肝动脉。结果近期疗效以CT检查结果作为评价标准,总有效率为54%66/122,平均生存期22.2个月。0.5、1、2、3年生存率分别是98.3%、80.4%、40.9%、10.6%。结论经肝动脉化疗药物灌注及栓塞治疗是失去手术机会的肝转移癌患者的一种安全、有效的姑息性治疗方法,其不仅能提高疗效,而且能改善患者的生活质量。Objective To evaluate the efficacy of selectiv e hepatic arterial infusion chemoth erapy and embolization in the treatm ent of unresectable liver metastases.Methods Percutaneous selective hepatic arterial infusion chemotherapy(Abriamycin,mitomycin,Cisplatin,5-fluorouracil)and embolization(mixture of iodic oil and ADM)was performed in 122patients with unresectable liver metastases.Results An overall response rate(CR +PR)of all cases after the teatment was 54%.The mean survival period of 122patients was 22.2months.The0.5-,1-,2-,and 3-year survival rat e was 98.7%,80.8%,40.9%,and 10.6%,respectively.Conclusion The hepatic artery in-fusion chemotherapy and embolization is a safe and effective palliative treatment for patients with unresec table liver metastases.[

关 键 词：肝动脉 灌注化疗 动脉栓塞 肝转移肿瘤 

分 类 号：R735.7[医药卫生—肿瘤]