应用Cox模型分析233例何杰金病的预后因素  

ANALYSIS OF PROGNOSTIC FACTORS OF HODGKIN'S DISEASE WITH COX MODEL

作　　者：归薇[1] 郑玉萍[1] 畅小琴[1] 张文丽[1] 麻生文 郭日升[1] 张文姝[1] 张巧花[1] 张俊萍[1] 侯淑玲[1] 

机构地区：[1]山西省肿瘤医院,山西省大同市第三医院

出　　处：《中华内科杂志》1994年第11期751-753,共3页Chinese Journal of Internal Medicine

摘　　要：应用Ｃｏｘ模型对何杰金病（ＨＤ）２３３例的预后因素进行了多因素比例危险率回归分析。从１９个变量中得出近期疗效、治疗剂量、病理类型、血沉降率、气短、临床分期和淋巴结肿大范围７个因素是影响ＨＤ预后的重要因素。he authors presented the application of the Cox proportional hazards stepwise regression procedure in prognostic factor analysis of Hodgkin,s disease.The data of 233 patients in our hospital from 1966 to 1989 were collected.there were 19 Variates used for univariate and multivariate analvsis,The result showed that seven variates were important prognostic factors of Hodgkin's disease, narnely;short-term effect,doses of treatment,pathological type,short breath, elevated ESR,clinical stage and lymphnode enlarge-ment.Among them,the probability of achieving complete remisson(CR)after initiaI treatment is a favor-able prognostic factor. Morever,the rate of CR is consistentlv associated with clinical stagedoses etc.It is important to make great efforts to avoid misdiagnosis. Early diagnosis and sufficient doses of medication are the crucial points for prolonged Survival.

关 键 词：何杰金病 预后 COX回归模型 

分 类 号：R733.107[医药卫生—肿瘤]