抗菌消炎片主要药效学研究  

Experimental study on main pharmacodynamics of Kangjun Xiaoyan Tablets

作　　者：马骏[1] 陈凌[2] 任远[1] 王志旺[1] 吴国泰[1] 

机构地区：[1]甘肃中医学院,甘肃兰州730000 [2]兰州医学院第二附属医院,甘肃兰州730030

出　　处：《中成药》2005年第6期687-690,共4页Chinese Traditional Patent Medicine

摘　　要：目的:对抗菌消炎片(金银花、百部、大黄等)的主要药效学进行研究。方法:通过抗菌、抗炎、解热和免疫功能测定等方法观察抗菌消炎片的药理作用。结果:抗菌消炎片对感染肺炎双球菌及感染金黄色葡萄球菌小鼠有明显保护作用;对蛋清所致大鼠足跖急性炎症和二甲苯所致小鼠耳廓急性炎症有明显的抗炎作用;对干酵母引起的大鼠发热反应有明显对抗作用;试验结果还显示抗菌消炎片可增强小鼠网状内皮系统的吞噬功能。结论:抗菌消炎片具有抗菌、抗炎、解热和增强免疫功能的作用。AIM: To study the mostly pharmacological effects of Kangjun Xiaoyan Tablets (Flos Lonicerae, Radix Stemonae, Radix et Rhizonia Rhei, etc.) METHODS: The pharmacological functions of KJXYT were observed by measuring its antibacterial, anti-inflammatory, antipyretic and immune etc. RESULTS: KJXYT had remarkably protected the mice from the infection with streptococcus pneumococcus and staphylococcus aureus; had dramatic anti-inflammatory effect on the inhibited feet edema of rat induced by egg white and the ear edema of mice induced by dimethylbenzene; and had obvious effect on fever of rats caused by dried yeast; besides, and strengthened the phagocytosis of mice’s reticuloendothelial system. CONCLUSION:KJXYT serves the function of antibiosis, anti-inflammation, antipyresis and immunpotentiation. enedth

关 键 词：抗菌消炎片 抗菌 抗炎 解热 增强免疫 

分 类 号：R285.5[医药卫生—中药学]