^(18)F-FDG分子符合探测成像联合增强CT对肺内病灶鉴别诊断的价值  

Study on differential diagnosis of solitary pulmonary nodule by FDG-MCD with enhanced CT scanning

作　　者：周崧雯[1] 周彩存[1] 郑迪[1] 刘进军[1] 李爱武[1] 严令华[1] 

机构地区：[1]上海市肺科医院肿瘤科

出　　处：《临床肿瘤学杂志》2005年第3期284-287,290,共5页Chinese Clinical Oncology

摘　　要：目的:评价氟化脱氧葡萄糖(18F FDG)分子符合探测成像(简称FDG MCD)及胸部增强CT对肺内良恶性病灶的鉴别诊断价值。方法:胸部X线平片上疑为周围型肺癌的肺部球形病灶90例,比较胸部FDG MCD显像、增强CT扫描和经皮肺穿刺检查的诊断价值。结果:FDG MCD诊断肺恶性肿瘤的敏感性和特异性分别为96.83%(61/63)和74.07%(20/27),而增强CT分别为90.48%(57/63)和85.19%(23/27)。胸部FDG MCD和增强CT均阳性时,诊断敏感性为87.30%(55/63),特异性为92.59%(25/27)。结论:FDG MCD联合CT增强扫描对周围性肺部病灶性质具有重要的鉴别诊断意义。Objective:To evaluate the diagnostic ability of FDG-MCD and enhanced CT scanning in solitary pulmonary nodules.Methods:Thoracic FDG-MCD and enhanced CT scanning were performed on 90 patients with solitary pulmonary nodule suspected lung cancer by chest X-ray. All these people were diagnosed by CT-guided fine-needle aspiration from October 2001 to August 2003.Results:The sensitivity and specificity of FDG-MCD for detection of malignant mass were 96.8%(61/63) and 74.07%(20/27) respectively, whereas those of enhanced CT scanning were 90.5%(57/63) and 85.2%(23/27). The combined positivity of the two testing modalities, cases where both FDG-MCD and CT were positive, yielded a sensitivity of 87.3%(55/63), and the specificity of them had increased to 92.59%(25/27).Conclusion:FDG-MCD with enhanced CT scanning are important diagnostic tools to the solitary pulmonary nodule.

关 键 词：氟化脱氧葡萄糖 分子符合探测成像 胸部增强CT 鉴别诊断 周围型肺癌 

分 类 号：R734.2[医药卫生—肿瘤]