血管内栓塞治疗脑动静脉畸形  

The Treatment of Cerebral Arteriovenous Malformation by Endovascular Embolization

作　　者：鲍洪[1] 丁轩[1] 吴开华[1] 招建华[1] 兰蒙[1] 左右[1] 李铁林[2] 舒航[3] 

机构地区：[1]暨南大学医学院附属第三医院珠海市人民医院神经外科,广东珠海519000 [2]南方医科大学附属珠江医院神经外科 [3]广东省人民医院神经外科

出　　处：《中国医师杂志》2005年第6期767-769,共3页Journal of Chinese Physician

摘　　要：目的研究血管内栓塞治疗脑动静脉畸形(cAVM)的临床疗效。方法在数字减影全脑血管造影监视下,经股动脉插管,采用微导管技术,α-氰基丙烯酸正丁酯(NBCA)栓塞剂对23例cAVM患者行血管内栓塞,一次栓塞6例,分次栓塞17例,共45人次。11例栓塞后行γ-刀治疗。结果23例患者,血管畸形团完全栓塞达6例,>95%4例,70%～95%9例,70%以下4例,术后出现头晕、头痛3例。随访23例,4例仍有癫痫发作,余临床症状均明显改善。结论血管内栓塞治疗cAVM安全有效,单纯栓塞可治愈部分cAVM,血管内栓塞结合γ-刀放射治疗,可提高其治愈率。Objective To study clinical therapeutic effect of endovascular embolization on cerebral arteriovenous malformation(cAVM). Methods In digital subtraction angiography (DSA), 23 patients suffering from cAVM were treated by endovascular embolization with NBCA through microduct technique. 6 cases were embolizated only one time, and 17 cases more than one time. 11 patients were treated with gamma knife after embolization. Results Among 23 patients, 6 cases of cAVM were embolizated completely, 4 cases more than 95%, 9 cases 75% to 95%, and 4 cases less than 70%. 3 patients occurred dizziness and headache after embolization. All patients were followed up after treatment, 4 cases had seizure, and the others' symptoms were obviously improved. Conclusion Endovascular embolization was a safe and effective method for treating cAVM, and combination of embolization and gamma knife could improve the clinical efficiency.

关 键 词：血管内栓塞治疗 脑动静脉畸形 数字减影全脑血管造影 Α-氰基丙烯酸正丁酯 γ-刀放射治疗 经股动脉插管 cAVM 微导管技术 Γ-刀治疗 临床疗效 血管畸形 癫痫发作 临床症状 栓塞剂 栓塞后 治愈率 患者 

分 类 号：R743.3[医药卫生—神经病学与精神病学]