75例先天性心脏病感染性心内膜炎的临床分析  

Analysis of the infective endocarditis in patients with congenital heart disease

作　　者：李玲[1] 韩宏光[1] 张南滨[1] 汪曾伟[1] 

机构地区：[1]沈阳军区总医院,辽宁沈阳市110016

出　　处：《心血管康复医学杂志》2005年第3期247-249,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨先天性心脏病(先心病)感染性心内膜炎(IE)的临床特点。方法:回顾性分析75例住院患者中各类先心病IE的并发率、临床特点、血培养、心内膜受累和治疗情况。结果:①先心病IE中主动脉瓣病变发病率最高(6.2%);②手术证实累及多个瓣膜,病变多样;③尿检查改变、肝大和脾大的发生率及血培养阳性率(35.7%) 较文献报道下降,可能与抗生素广泛应用和感染的主要致病微生物与过去不同有关;④手术治疗45例,治愈44例(97.8%),死亡1例,内科治疗30例,治愈13例(43.3%),因动脉栓塞或心功能恶化而出院14例,死亡3例。结论:适当的内科治疗与积极的外科治疗相结合对提高先心病IE存活率、降低病死率有重要意义。Objective: To investigate the clinical characteristics of infective endocarditis (IE) in patients with congential heart disease (CHD). Methods: The data of 75 CHD patients complicated with IE were analyzed. Results:In 75 CHD patients complicated with IE: The incidence of aortic valve lesion was the highest (6.2%). The incidences of hepatomegaly, splenomegaly and positive blood culture (35. 7%) were reduced compared with literature. Surgery was performed in 45 cases,one case died and 44 cases were cured(97. 8%). The other 30 cases received medical treatment, out of them 13 were cured (43. 3%), 4 cases died. Conclusion:Appropriate medical treatment combined with active surgical treatment plays an important role in the treatment of CHD patients complicated with IE.

关 键 词：感染性心内膜炎 先天性心脏病 临床分析 主动脉瓣病变 临床特点 内科治疗 回顾性分析 致病微生物 先心病 住院患者 治疗情况 手术证实 文献报道 手术治疗 动脉栓塞 外科治疗 重要意义 血培养 IE 发病率 尿检查 阳性率 发生率 

分 类 号：R542.42[医药卫生—心血管疾病] R541.1[医药卫生—内科学]