Nodal spread and micrometastasis within mesorectum  

作　　者：CunWang Zong-GuangZhou ZhaoWang Dai-YunChen Yang-ChunZheng Gao-PingZhao 

机构地区：[1]DepartmentofGeneralSurgery,WestChinaHospital,SichuanUniversity,Chengdu610041,SichuanProvince,China [2]DepartmentofPathology,WestChinaHospital,SichuanUniversity,Chengdu610041,SichuanProvince,China

出　　处：《World Journal of Gastroenterology》2005年第23期3586-3590,共5页世界胃肠病学杂志（英文版）

基　　金：Supported by the Grants From the Key Project of National Outstanding Youth Foundation of China,No.39925032

摘　　要：AIM: To study the distribution of positive lymph nodes within mesorectum and to investigate the possible micrometastasis in negative lymph nodes. METHODS: Large slice technique combined with tissue microarray was used in the pathologic study of 31 specimens.RESULTS: A total of 992 lymph nodes were harvested and cancer metastasis was found in 148 lymph nodes. Some positive lymph nodes were located in the outer layer of mesorectum and more at the same site of mesorectum as the primary tumor. Circumferential margin lymph node metastasis was observed in nine cases. No significant difference in occurrence of micrometastasis was observed in different stage tumors. CONCLUSION: Positive lymph nodes are distributed in mesorectum and micrometastasis can be found in negative lymph nodes.AIM:To study the distribution of positive lymph nodes within mesorectum and to investigate the possible micrometastasis in negative lymph nodes. METHODS:Large slice technique combined with tissue microarray was used in the pathologic study of 31 specimens. RESULTS:A total of 992 lymph nodes were harvested and cancer metastasis was found in 148 lymph nodes. Some positive lymph nodes were located in the outer layer of mesorectum and more at the same site of mesorectum as the primary tumor. Circumferential margin lymph node metastasis was observed in nine cases. No significant difference in occurrence of micrometastasis was observed in different stage tumors. CONCLUSION: Positive lymph nodes are distributed in mesorectum and micrometastasis can be found in negative lymph nodes.

关 键 词：Rectal cancer MESORECTUM Lymph node 

分 类 号：R735.4[医药卫生—肿瘤]