翼状胬肉切除术后应用贝复舒与爱丽滴眼液疗效对比观察  

A comparison of therapeutic effects between rb-bFGF and Hialid in the treatment post pterygium excision

作　　者：李强[1] 万鹏霞[1] 

机构地区：[1]广州市花都区人民医院眼科,510800

出　　处：《临床眼科杂志》2005年第3期242-243,共2页Journal of Clinical Ophthalmology

摘　　要：目的评价翼状胬肉切除术后应用贝复舒与爱丽眼液对角膜上皮缺损修复、角膜透明度的改善及预防胬肉复发的疗效比较。方法将翼状胬肉切除术后患者110例(132只眼)按随机方式分成3组,贝复舒组40只眼,爱丽组40只眼,对照组52只眼,术后定期观察角膜上皮修复情况及胬肉复发情况,随访时间为半年。结果贝复舒与爱丽眼液均有促进角膜上皮修复的作用,贝复舒作用更强(P<0.01);对改善术后角膜透明度的方面,贝复舒作用最明显与对照组差异显著(P<0.05),而爱丽组与对照组差异无显著性(P>0.05);术后6月,贝复舒组无一眼复发,爱丽组2只眼复发(5.00%),对照组9只眼复发(17.31%)。结论贝复舒眼液用于翼状胬肉术后,能促进角膜上皮快速修复,改善角膜透明度,预防术后翼状胬肉复发有一定作用。Objective To evaluate the therapeutic effects of the eye drops of rb-bFGF and Hialid in the treatment post pterygium excision. We observe the epithelial healing of the corneal, the transparency of the corneal and the recurrence of pterygium. Method The 110 patients (132 eyes) who have had pterygium excision were divided into 3 groups randomly: 40 eyes in the rb-bFGF group, 40 eyes in the Hialid group, and 52 eyes in the control group. We observe the epithelial healing of the corneal and the recurrence of pterygium. The post operation follow-up period is half a year. Results Both of rb-bFGF and Hialid have the function of accelerate the epithelial healing of the corneal. But the effect of the eye drops of rb-bFGF is more powerful (P<0.01); On the improvement of the transparency of the corneal post operation, the difference between the rb-bFGF group and the control group is significant (P<0.05). But the difference between the Hialid group and the control group is not significant (P>0.05). 6 months after the operation, there is no eye recurred in the rb-bFGF group, 2 eyes in the Hialid group (5.00%) and 9 eyes in the control group (17.31%) recurred. Conclusion The therapeutic effects of the eye drops of rb-bFGF used post pterygium excision are definite. It can not only accelerate the epithelial healing of the corneal, but also improve the transparency of the corneal. Further more, it can prevent the recurrence of pterygium. It's worth using.

关 键 词：翼状胬肉切除 术后应用 疗效对比观察 爱丽滴眼液 角膜上皮修复 角膜透明度 贝复舒眼液 对照组 缺损修复 疗效比较 术后患者 复发情况 随访时间 差异显著 胬肉术后 快速修复 显著性 预防 

分 类 号：R779.6[医药卫生—眼科]