根治性胆囊切除术对胆囊癌患者营养水平的影响  

The effect of radical cholecystectomy on nutritioual status in patients with gallbladder carcinoma

作　　者：焦兴元[1] 石景森[1] 于跃利[1] 刘刚[1] 韩玥[1] 

机构地区：[1]西安医科大学第一临床医学院肝胆外科研究室,710061

出　　处：《中国临床营养杂志》2000年第1期8-9,共2页Chinese Journal of Clinical Nutrition

摘　　要：目的探讨根治性胆囊切除术对胆囊癌患者营养水平的影响。方法27例行根治性胆囊切除术的胆囊癌患者，分别于术前和术后第三天、第一周、第二周及第三周测定血清白蛋白、胆固醇、总铁结合量、转铁蛋白、铁、镁、锌浓度。结论术后第三天，所有的营养评估指标均急剧下降（P＜0．01）。术后二～三周，血清白蛋白、镁、锌浓度已恢复到术前水平，但血清铁、转铁球蛋白和血清总铁结合量在术后第三周仍未恢复。结论胆囊场根治性切除术对患者营养水平的影响是暂时的和可逆转的，患者应补充足量的铁，同时要定期检查血清微量元素水平。objective To evaluate the peri-operative sequential changes in patients in nutritbol status. Mothods Twenty-seven patients with early gallbladder carcinoma who had undergone radical cholecystectomy were studied.The nutritional assessment were performed praperatively,on the postoperative day3,7, 14 and 21. Results All the parameters in nutritional assessment declined greatly by post-operative day 3 (P< 0. 01 ). Most of them returned to the preoperative levels within 2 ~ 3 weeks after surgery. However, the serum levels of iron, transferrin and TIBC did no return to normal in the third post-operative week. Conclusious Radical cholecystectomy for early gallbladder carcinoma might have only temporarily effect on the host nutritional parameters returned to the preoperative level within second and third weeks after surgery. An adequate supplementation of iron is needed after the second poSt-operative week. It is very necessary for monitoring the serum minerals levels after surgery.

关 键 词：胆囊切除术 营养水平 癌患者 血清白蛋白 根治性切除术 微量元素水平 转铁球蛋白 转铁蛋白 评估指标 定期检查 结合量 锌浓度 术后 胆固醇 血清铁 可逆转 胆囊癌 术前 总铁 恢复 

分 类 号：R735.8[医药卫生—肿瘤]