CT结合内镜检查诊断胃肠道间质瘤的价值  

Analysis of the Value of CT and Endoscopy in Diagnosing Gastrointestinal Stromal Tumors

作　　者：谢东[1] 苏丹柯[1] 周小燕[1] 金观桥[1] 李强[1] 张昱苹[1] 

机构地区：[1]广西医科大学附属肿瘤医院,广西南宁530021

出　　处：《四川肿瘤防治》2005年第2期75-77,共3页Sichuan Journal of Cancer Control

摘　　要：目的探讨CT结合内镜检查诊断胃肠道间质瘤(GIST)的价值。方法回顾分析18例均经手术病理检验证实为GIST病人的CT及内镜检查资料。结果(1)18例GIST的CT表现为类圆形或分叶状肿瘤,边界清楚,13例平扫及增强密度均匀,强化明显,5例瘤灶内有坏死液化区;肿瘤周围肠管不同程度受压移位或粘连。(2)15例源于胃、十二指肠及结肠的间质瘤均行内镜检查,4例瘤侧胃壁镜下所见黏膜呈外压性改变者未行咬检;11例伴有溃疡形成,溃疡处咬检获取病理组织。(3)18例均行手术后光镜观察及免疫组化检查,18例CD117均为阳性,13例CD34阳性,10例Vimentin阳性。结论CT与内镜相结合检查,能提高胃、十二指肠及结肠GIST定位、定性的准确性。Objective: ?To investigate the value of CT and endoscopy in the diagnosis of gastrointestinal stromal tumors(GIST). Methods: ?18 cases with GISTs which have been proved by postsurgical pathology were retrospectively analyzed. Results: ?(1)CT examination revealed that the tumors showed oval or multilobular in shape with well-defined margin in all 18 cases.13 cases showed homogeneous in density on CT plain and post-contrast scans,and markedly enhanced homogeneously;5 cases showed necrosis in the tumors.The alimentary tracts neighboring the tumors were compressed,displace or adhered.(2)15 cases GISTs arising in stomach,duodenum or colon were examined by endoscopy;4 cases were observed to have prominence due to extrinsic depression on mucous membranes of gastric wall,so biopsy was not taken.11 cases companied with ulcer,were taken biopsy.(3)18 cases were examined by light microscopy and immunohistochemistry after operation,all 18 cases were positive for CD117,13 for CD34,10 for Vimentin. Conclusion: ?CT plus endoscopy examination can improve the accuracy of diagnoss of GISTs. [

关 键 词：胃肠道间质瘤 检查诊断 价值 Vimentin GIST 免疫组化检查 十二指肠 检查资料 手术病理 回顾分析 叶状肿瘤 CT表现 坏死液化 不同程度 肿瘤周围 内镜检查 溃疡形成 病理组织 光镜观察 外压性 溃疡处 手术后 阳性 准确性 

分 类 号：R735[医药卫生—肿瘤] R695.8[医药卫生—临床医学]