脑梗塞患者血液流变学变化  

Changes of Hemorheology in the Cerebral Infarction

作　　者：曹伟建[1] 钱义兵[1] 

机构地区：[1]安徽省立医院

出　　处：《中国血液流变学杂志》2005年第1期69-70,共2页Chinese Journal of Hemorheology

摘　　要：目的　探讨血液流变学指标在脑梗塞(CI)中的变化规律及其致病机理。方法　测定15 8例CI患者血液流变学6项指标[全血低切和高切粘度、血浆粘度、红细胞压积(HCT)、血沉(ESR)和纤维蛋白原],并与正常对照组比较。结果　CI患者两性全血低切和高切粘度、血浆粘度以及纤维蛋白原均高于正常对照组(P <0 .0 5 ,P <0 .0 0 1) ;两性HCT与正常对照组比较差异无显著性(P >0 .0 5 )。结论　血液流变学异常是CI的病理机制之一;血浆纤维蛋白原增高是造成CI患者血液粘度升高的主要因素之一。Objective To investigate the hemorheological alterations and pathogeneses of the patients with the cerebral infarction.Methods The hemorheological indexes such as low shear and high shear viscosity of the whole blood,plasma viscosity,hematocrit(HCT),erythrocyte sedimentation(ESR) and fibnnogen were measured in 158 cases of the patients with the cerebral infarction and were compared with those of the normal controls.Results Low shear and high shear viscosity of the whole blood,plasma viscosity and fibrinogen of the cerebral infarction groups were significantly higher than those of the normal control groups and HCT had no notable variation.Conclusions Abnormal variations of hemorheology were one of the pathogeneses of the cerebral infarction and elevated fibrinogen levels were one of the main factors leading to an increase in blood viscosity.

关 键 词：脑梗塞 血液流变学 

分 类 号：R743.33[医药卫生—神经病学与精神病学]