难治性癫痫的24小时脑电监测临床意义  

Clinical value of twenty-four hour ambulatory EEG monitoring on refractory epilepsy

作　　者：童晓欣[1] 苏曼[1] 

机构地区：[1]北京大学深圳医院神经内科,广东深圳518036

出　　处：《中国基层医药》2005年第5期513-514,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨24h脑电(AEEG)监测对难治性癫痫的临床意义。方法对96例难治性癫痫患者进行连续24hAEEG监测。结果AEEG痫波阳性率为64.29%,与常规EEG的28.21%相比较,差异有极显著意义(P<0.001)。且痫样放电与睡眠密切相关。96例患者中捕获41例(42.71%)临床发作,其中31例确诊为癫痫发作;2例癫痫合并假性发作;3例假性发作;3例睡眠呼吸暂停综合征(SAS);2例癫痫合并SAS。结论24hAEEG携带方便,监测期间自然睡眠不受环境改变的影响,显著提高了临床癫痫发作和痫样放电阳性率,还可作为难治性原因之一SAS的筛查检测,有助于难治性癫痫的诊断和鉴别诊断。Objective To evaluate the clinical value of twenty-four hour ambulatory EEG(AEEG) monitoring on refractory epilepsy.Methods Continuous AEEG monitoring was performed on 96 patients with refractory epilepsy.Results The positive rate of epileptiform discharges was 64.29%,which had extremely significant difference(P<0.001) compared with a rate of 28.21% of routine EEG,and epileptiform discharges were closely related to sleep.The seizure episodes were captured in 41(42.71%) of the 96 patients,and among them 31 were diagnosed epilepsy;2 were diagnosed epilepsy accompanied by pseudoseizure(PS);3 were diagnosed PS;3 were diagnosed sleep apnea syndrome(SAS);2 were diagnosed epilepsy accompanied by SAS.Conclusion 24h AEEG can significantly increase the positive rate of seizure episodes and epileptiform discharges.It can also be applied as a screen to one of the refractory causes of SAS.So it plays an important role in the diagnosis,differential diagnosis and guide to therapy.

关 键 词：难治性癫痫 临床意义 脑电监测 睡眠呼吸暂停综合征 诊断和鉴别诊断 痫样放电 癫痫发作 假性发作 24h脑电 EEG监测 癫痫患者 AEEG 临床发作 环境改变 自然睡眠 阳性率 SAS 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R766.43[医药卫生—临床医学]