短瓣金莲花的化学成分研究  

Study on chemical constituents of Trollius ledebouri

作　　者：邹建华[1] 杨峻山[1] 

机构地区：[1]中国医学科学院-中国协和医科大学药用植物研究所,北京100094

出　　处：《中国药学杂志》2005年第10期733-736,共4页Chinese Pharmaceutical Journal

摘　　要：目的对毛茛科金莲花属植物短瓣金莲花(TrolliusledebouriReichb.)的花进行化学成分研究。方法利用溶剂提取、硅胶色谱柱和SephadexLH-20反复进行分离纯化,波谱法鉴定结构。结果分离到14个已知化合物,分别为棕榈酸(Ⅰ)、二十四烯(Ⅱ)、β-谷甾醇(Ⅲ)、鼠尾草素(Ⅳ)、藜芦酸(Ⅴ)、香草酸(Ⅵ)、玄参黄酮(Ⅶ)、胡萝卜苷(Ⅷ)、对羟基苯甲酸甲酯(Ⅸ)、白杨黄酮(Ⅹ)、对羟基苯甲酸(Ⅺ)、木犀草素(Ⅻ)、槲皮素(ⅩⅢ)、日本椴苷(ⅩⅣ)。结论除化合物Ⅰ,Ⅲ和Ⅴ以外,其余化合物均为首次从该属植物中分离得到。OBJECTIVE: To study the chemical constituents from the flower of Trollius ledebouri. METHODS: The components were separated by means of solvent extraction, repeated chromatography with silica column and Sephadex LH-20. The structures were determined by spectral analysis. RESULTS: Fourteen compounds were isolated as palmitic acid(I), tetracosene(II), β-sitosterol(III), salvigenin(IV), veratric acid(V), vanillic acid(VI), scrophulein(VII), daucosterol(VIII) , methyl P-hydroxybenzoate(IX), chrysoeriol(X), 4-hydroxybenzoic acid(XI), luteolin(XII), quercetin(XIII) and tilianin(XIV). CONCLUSION: All compounds except I, III, and V were isolated from the genus Trollius for the first time.

关 键 词：短瓣金莲花 黄酮 有机酸 

分 类 号：R284.2[医药卫生—中药学]