兔胸主动脉在冻结状态下力学性能的实验研究  

Experimental study on the mechanical properties of frozen rabbit aorta

作　　者：胥义[1] 周国燕[1] 胡桐记[1] 高才[1] 华泽钊[1] 

机构地区：[1]上海理工大学动力工程学院,上海200093

出　　处：《上海理工大学学报》2005年第3期198-202,共5页Journal of University of Shanghai For Science and Technology

基　　金：国家自然科学基金重点资助项目(50436030);国家自然科学基金青年基金资助项目(50206013);上海市教委青年基金资助项目(02GQ25)

摘　　要：采用动态机械分析仪(DMA)研究了不同的温度点、降温速率以及低温保护剂浓度对兔胸主动脉在冻结状态下力学性能的的影响.研究结果表明,未经二甲基亚砜(DMSO)处理过的主动脉血管在-50℃的断裂强度(11.62±0.51MPa)和弹性模量(2670±1360MPa)均明显比-20℃时的断裂强度(8.71±0.44MPa)和弹性模量(37.1±4.65MPa)大,而且也要略高于-80℃时的断裂强度(10.18±3.2MPa)和弹性模量(2050±690MPa);以20℃/min降温时的弹性模量略低于5℃/min降温时的弹性模量,但其断裂强度反而略高;随着DMSO浓度增大,弹性模量显著减小,而且其断裂强度也会逐渐减小,但当DMSO浓度增大到一定值时,这种变化不再明显.To obtain the mechanical properties parameters for frozen rabbit aorta, the effects of temperatures, cooling rates and cryoprotective agent's concentrations on the mechanical properties of frozen rabbit aorta were investigated with Dynamical Mechanical Analyser (DMA2980). The experimental results show that the fracture strength and elastic modulus of rabbit aorta without MDSO at-50°C are obviously higher than those at-20°C, and also a bit higher than those at-80°C; the elastic modulus with the cooling rate of 20°C/min is a bit lower than that with the cooling rate of 5°C/min, but the fracture strength is in reverse; with the increasing concentration of DMSO, the elastic modulus decreases markedly, and the fracture strength will also become smaller gradually, however, this change will be no more obvious when the concentration of DMSO rises to some point (e.g. 10%).

关 键 词：兔胸主动脉 冻结 力学性能 二甲基亚砜(DMSO) 

分 类 号：R318.52[医药卫生—生物医学工程] R318.11[医药卫生—基础医学]