骨刺消胶囊中阿魏酸的HPLC测定  

Content Determination of Ferulic Acid in Gucixiao Capsules by HPLC

作　　者：王隶书[1,2] 程东岩[1,2] 严玉清[1,2] 

机构地区：[1]吉林省中医中药研究院,长春130021 [2]吉林省人民医院

出　　处：《中国药师》2005年第7期564-565,共2页China Pharmacist

摘　　要：目的:建立骨刺消胶囊中阿魏酸的含量测定方法。方法:HPLC法,日本岛津ODS C18柱(4.6 mm×150 mm,5μm), 流动相:乙腈-0.4%磷酸溶液(13.5:86.5);检测波长为315 nm;柱温40℃。结果:阿魏酸线性范围为0.051-0.51 μg,平均回收率。100.5%,RSD为1.83%。结论:方法可靠,简单可行,为控制骨刺消胶囊的质量提供了科学依据。Objective: To set up a method for determining ferulic acid in Gucixiao capules. Method: HPLC,the shimadzu ODS C18 column (4. 6 mm ×2. 50 mm,5 μm) was used, mobile phase: Acetonitrile-0. 4% phosphoric acid solution( 13. 5: 86. 5 ) ,detecting wavelength:315 nm. Result: The standard curve was linear within a range of 0.051-0.51 μg. The average recovery and RSD were 100. 5% and 1. 83% respectively. Conclusion: This method is accurate,reliable and provides a scientic index for controlling the quality of Gucixiao capsules.

关 键 词：骨剌消胶囊 阿魏酸 高效液相色谱法 

分 类 号：R927.11[医药卫生—药学]