生物活性玻璃陶瓷种植材料与牙龈上皮细胞体外界面的超微结构研究  

Ultrastructural Study of Epithelial Cells Attachment to BGC Implant Materials

作　　者：石虹[1] 陈安玉[1] 

机构地区：[1]华西医科大学口腔医学院

出　　处：《华西口腔医学杂志》1994年第1期56-59,T004,共5页West China Journal of Stomatology

摘　　要：采用牙龈上皮细胞体外培养方法，对国产生物活性玻璃陶瓷（ＢＧＣ）的牙龈界面，进行了超微结构观察分析。结果发现：透射电镜（ＴＥＭ）下ＢＧＣ与上皮细胞界面结合形式有三种，其中半桥粒结构被认为在上皮附着材料中起重要的结合作用；扫描电镜（ＳＥＭ）及Ｘ线能谱分析（ＥＤＡＸ）发现上皮细胞在ＢＧＣ上生长良好。结果表明：ＢＧＣ能够与牙龈上皮形成良好界面。粘膜封闭的形成保证了种植体在口腔内的长期成功。Abstract The objective of this study, was to gain insight into the morphology of epithelial cell-implant interface for bioactiveglass implant materials using TEM, SEM, EDAX. Human embryo gingival epithelial cells were cultured on bioglass ceramic (BGC) . The cultures on BGC were decalcified prior to sectioning. The results revealed that as attachment structures,hemidesmosomes contact, focal contact, extracellular matrix contact could be distinguished on BGC materials surface and epithelial cells had normal surface mophology including mocrovilli. Also there were no changes on elements of BGC during 16～21 days culture.The results of this study suggest the property of the subtrate that determines the nature and the structure of the contact site with epithelial cells is able to secure the permucosal seal.

关 键 词：生物玻璃陶瓷 牙龈 超微结构 

分 类 号：R783.1[医药卫生—口腔医学]