6例透明细胞肉瘤的临床病理及免疫组化观察  

Clinicopathological and Immunohistochemical Study of 6 Cases of Clear Cell Sarcoma

作　　者：杨举伦[1] 蔡琳[1] 冯毓正[2] 邹红[1] 罗学林[1] 

机构地区：[1]成都军区昆明总医院病理科,云南650032 [2]昆明医学院附一院病理科,云南650032

出　　处：《临床与实验病理学杂志》1994年第4期307-308,T006,共3页Chinese Journal of Clinical and Experimental Pathology

摘　　要：对6例罕见的透明细胞肉瘤作了光镜和免疫组化观察。光镜下瘤细胞呈多边形,胞界不清,胞浆丰富透明、含PAS阳性物。核大,空泡状,核仁大。瘤细胞聚集成条索状或片块状,由纤维组织分隔。6例均表现为NF、NSE、S-100、α_1-AT、Lysozyme阳性和Fibronectin、Vimentin、Desmin、Cytokeratin、CEA阴性。我们的资料支持该瘤起源于神经嵴的观点。The clinicopathologic and im-munohistochemical features of 6 cases of clear cell sarcoma were discribed. The tumor cell tended to be polygonal and round with plenty of clear cytoplasm, a few PAS positive granules, a large bubbly nucleus and a large mucleole. The cells were arranged in strands and nests displaying uncertain cell-cell bordors. All of 6 cases showed positive reaction with antibodies of s-100 protein, NF, NSE, a-AT, lysozyme, but negative reaction with antibodies of FN, CEA, vimentin, desmin, cytokeratin. The immunohistochemical results support the neural crest origin of this tumor.

关 键 词：透明细胞肉瘤 免疫组织化学 软组织肿瘤 

分 类 号：R738.602[医药卫生—肿瘤]