腹膜神经胶质瘤病  

Gliomatosis peritonei

作　　者：陶瑜[1] 胡媛芳[1] 

机构地区：[1]广州中山医科大学病理学教研室

出　　处：《中华病理学杂志》1994年第2期76-78,T015,共4页Chinese Journal of Pathology

摘　　要：腹膜神经胶质瘤病是卵巢实性畸胎瘤合并神经胶质组织的腹膜种植现象。报道的８例中，活检时平均年龄１７．４岁。卵巢畸胎瘤最大直径是３０ｃｍ，平均２１．４ｃｍ。５例的肿瘤包膜局部缺损或与邻近脏器粘连。１例卵巢畸胎瘤术后１０个月，二次手术时发现腹膜播散。我们认为肿瘤包膜的缺损是导致腹膜播散的主要原因。腹膜种植结节总是由胶质纤维酸性蛋白和Ｓ－１００蛋白阳性并成熟的神经胶质组织组成。本组的平均随访期３６．２个月。其中病例２已存活８年３个月。提示腹膜神经胶质瘤病可能促进卵巢实性畸胎瘤的良性逆转。liomatosis peritonei(GP)is the implantation of glial tissue on the peritoneal surface in patients with solid ovarian teratoma.The average age at time of biopsy was 17.4 years in this study.The largest ovarian teratoma was 30cm in diameter with an average of 21.4cm.The tumor capsules were ruptured and adhered to the omentum in 5 cases.Peritoneal dissemination was detected in one patient at the sec-ond operation 10 months after the first one.It's believed that injury to the tumor capsule may have a role in peritoneal implantation. In general,regardless of the grade of the primary ovarian teratoma,the im-planted peritoneal nodules consisted exclusively of GFAP and S～100 protein positive mature astroglia The average length of follow up was 36.2months.One patient with GP is alive and clinically heaIthy 8 vears and 3 months post-operatively. The authors consider GP is a benign condition and associated with an improved prognosis for soiid ovarian teratoma.

关 键 词：卵巢 腹膜 神经胶质瘤病 病理 

分 类 号：R737.310.2[医药卫生—肿瘤]