脑出血致多脏器功能障碍综合征的临床研究  

Clinical Research of Multiple Organ Dysfunction Syndrome Induced by Cerebral Hemorrhage

作　　者：陈士军[1] 黄红丽[1] 徐锋[1] 周炳华[1] 

机构地区：[1]徐州医学院附属市立医院神经科,221002

出　　处：《神经疾病与精神卫生》2005年第2期116-117,共2页Journal of Neuroscience and Mental Health

摘　　要：目的探讨脑出血致多脏器功能障碍综合征(MultipleOrganDysfunctionSyndrome,MODS)的发生机制、临床表现、防治措施及预后。方法总结2002年6月～2004年12月我院脑出血住院病人资料,并分为出血量≥30ml组及<30ml组;破入脑室组及未破入脑室组,分别统计其发生MODS例数,以及发生MODS后死亡例数。结果206例脑出血患者86例发生MODS,68例出血量≥30ml组发生MODS62例,134例出血量<30ml组21例发生MODS,二者比较有极显著性差异(P<0.01);56例破入脑室系统组51例发生MODS,153例未破入脑室系统组35例发生MODS,二者比较有极显著性差异(P<0.01);86例发生MODS死亡32例,123例未发生MODS死亡5例,二者比较亦有极显著性差异(P<0.01)。结论脑出血后易发生MODS,尤以出血量大及破入脑室系统为著,且是导致死亡的主要原因,治疗上要采用“鸡尾酒疗法”综合、序贯治疗。Objective To probe the mechanisms, clinical manifestation, prevention measures and prognosis of multiple organ dysfunction syndrome (MODS) induced by cerebral hemorrhage.Methods Summarizing the data of hospital patients with cerebral hemorrhage in our hospital from June 2002 to December 2004, all patients were grouped according to hemorrhage volume and blood breaking into cerebral ventricle or not. The cases of patients with MODS and the number of death were accounted. Results In 206 cases of patients with cerebral hemorrhage, 86 cases with MODS, in 68 cases with more than 30ml hemorrhage, 62 cases with MODS, but in 134 cases with less than 30 hemorrhage, only 21 cases with MODS, there were significant difference (P<0.01). 56 cases with blood breaking into cerebral ventricle and 51 cases with MODS, 153 cases with blood not breaking into cerebral ventricle and 35 cases with MODS, the difference was significant (P<0.01). 86 cases with MODS and 32 cases died, 123 cases without MODS and only 5 cases died, the difference was significant too (P<0.01). Conclusions MODS is easy to occur after cerebral hemorrhage, especially in the conditions of more hemorrhage and blood breaking into cerebral ventricle, it is the main cause of inducing death. Cocktail treatment was the main methods.

关 键 词：脑出血 多脏器功能障碍综合征 鸡尾酒疗法 

分 类 号：R743.34[医药卫生—神经病学与精神病学]