淋巴瘤骨髓侵犯临床特点分析  

Study on the clinical characteristics of lymphoma patients with bone marrow infiltration

作　　者：马静秋[1] 梁辉[1] 董戴玉[1] 严云[1] 卞锦国[1] 杨镜明[1] 

机构地区：[1]第二医科大学附属新华医院血液内科,上海200092

出　　处：《临床血液学杂志》2005年第4期226-228,共3页Journal of Clinical Hematology

摘　　要：目的:探讨淋巴瘤骨髓侵犯的临床特点、治疗效果和预后。方法:对31例淋巴瘤病例的骨髓和其他淋巴结区及结外器官的不同侵犯特点进行归类,分析不同类型淋巴瘤病例的治疗效果、生存率等临床特点差异。结果:从治疗效果分析,淋巴瘤以骨髓侵犯为惟一表现者(A组)及骨髓侵犯并发单个淋巴结区或单个结外器官浸润者(B组)预后较好;骨髓侵犯并发多个淋巴结区及(或)结外器官浸润者(C组)预后较差(P<0.01)。C组1年生存率最低(55%),余2组均为100%(P<0.01)。结论:淋巴瘤骨髓侵犯患者的治疗效果及生存率与淋巴结区及结外器官浸润范围有关。Objective:To analyze the clinical characteristics, therapeutic efficacy and prognosis of lymphoma patients with bone marrow infiltration. Method:To classify 31 cases of lymphoma patients according to their different infiltrative characteristics into bone marrow and other lymph node regions or extranodal organs, and to analyze the difference of their therapeutic efficacy and survival rate. Result:Lymphoma patients verified by bone marrow puncture and biopsy without any infiltration evidence in other sites (group A) and those with bone marrow and single lymph node region or extranodal organ infiltration (group B) had the better clinical outcome. The rest (group C)with bone marrow and extensive infiltration had the worse therapeutic efficacy(P<0.01). One-year-survival-rate of group C was 55% and the other two groups were 100%(P<0.05). Conclusion:The therapeutic efficacy and survival rate of patients with bone marrow infiltration related to the infiltration coverage of lymph node regions and extranodal organs.

关 键 词：淋巴瘤 骨髓侵犯 治疗效果 预后 

分 类 号：R733.4[医药卫生—肿瘤]