^(18)F-FDG SPECT显像在孤立肺结节中的诊断价值  

To investigate the clinical significance of ^(18)F-FDG SPECT/CT imaging in diagnosis of solitary pulmonary nodule

作　　者：缪珑昇[1] 相加庆[1] 张碧媛[2] 胡鸿[1] 马龙飞[1] 施伟[3] 

机构地区：[1]复旦大学附属肿瘤医院胸外科 [2]复旦大学附属肿瘤医院放疗科 [3]复旦大学附属肿瘤医院核医学科

出　　处：《中国癌症杂志》2005年第3期241-243,共3页China Oncology

摘　　要：目的:探讨18F-FDGSPECT显像在孤立肺结节(SPN)中的诊断价值。方法:2003年7月至2004年12月其间,应用具有PET/CT功能的SPECT显像技术对32名孤立性肺结节病例进行18F-FDG检查,同时行CT检查,两者的结果均与术后病理进行比较,从而评价18F-FDGSPECT显像的诊断价值。结果:32例病例中病灶直径大于2cm的为17例,小于2cm的为15例。SPECT对于病灶大于2cm的敏感性100%,特异性60%,准确性88%,阳性预测值86%,阴性预测值100%,病灶小于2cm的敏感性88%,特异性86%,准确性87%,阳性预测值88%,阴性预测值86%,阳性似然比6.13,阴性似然比0.15。CT的敏感性60%,特异性41%,准确性53%,阳性预测值63%,阴性预测值38%。结论:18F-FDGSPECT显像在孤立肺结节的诊断中有很好的应用价值,并且对于直径大于2cm的病灶有更高的敏感性和阴性预测值。Purpose:Thirty-two patients underwent ~ 18F-FDG SPECT/CT imaging and CT, the results of SPECT and CT were compared with the postoperative pathologic findings. Methods:There were 20 malignant lesions and 12 benign lesions.average sensitivity,specificity, accuracy, positive predictive value, and negative predictive value of SPECT were, 100%,60%,88%,86%,and 100% for lesions> 2 cm in size,88%,86%,87%,88%,and 86% for lesions 1 to 2 cm in size respectively . Sensitivity ,specificity, accuracy, positive predictive value, and negative predictive value of CT were 60%, 41%, 53%, 63%, 38% respectively. Results:. Conclusions:~ 18F-FDG SPECT/CT imaging is of great value in clinical use because of its high sensitivity and negative predictive value, especially for lesions > 2 cm in size.

关 键 词：SPECT 孤立肺结节 CT 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]