实时谐波超声造影在肝肿瘤消融治疗中的应用  

Usefulness of contrast Harmonic Sonography in the Treatment of Liver neoplasms with Radiofrequency Ablation

作　　者：罗葆明[1] 文艳玲[1] 智慧[1] 段红艳[1] 杨海云[1] 冯霞[1] 

机构地区：[1]中山大学附属第二医院超声科,广州市510120

出　　处：《中国超声医学杂志》2005年第7期522-524,共3页Chinese Journal of Ultrasound in Medicine

基　　金：广东省自然科学基金(No.31710);广东省卫生厅医学科研项目(No.A2003203)资助

摘　　要：目的探讨实时谐波超声造影在肝肿瘤消融治疗中的价值。方法对112例肝脏局灶性占位病变患者进行实时超声谐波造影、增强CT/MR和/或病理检查。34例进行了手术治疗,32例进行了射频消融治疗。结果实时谐波超声造影诊断肝脏恶性肿瘤的敏感性、特异性和准确性分别为97.1%、95.3%和96.4%。超声造影显示病灶数增加,病灶范围增大;射频消融后10min和1个月超声造影分别有5例和3例患者见动脉早期病灶部分强化。病灶最大直径超声造影测值与手术标本测值无差异。结论超声造影有助于肝脏肿瘤非手术治疗适应证的选择,提高引导穿刺的准确性和确定治疗范围,以及术后疗效监测。Objective To evaluate the usefulness of contrast harmonic sonography(CHS) in the treatment of liver neoplasms with radiofrequency ablation(RFA).Methods One hundred and twelve patients with liver occupying lesions were examined by CHS,enhanced CT/MR and/or pathology.Thirty-two cases were treated by RFA and 34 were treated by operation.Results The sensitivity,specificity and accuracy of diagnosing malignant liver tumors by CHS was 97.1%,95.3% and 96.4% respectively.The number and size of the lesions were increased on CHS compared with those on conventional two-dimensional sonography.Early arterial enhancement was observed in five cases in ten minutes and in three cases one month after RFA.The size of the lesions measured on CHS was similar to the actual value of the operative samples.Conclusions CHS is helpful in choosing the indicators of non-operative treatment methods,guiding punctures,determining the therapeutic scope and evaluating the therapeutic response.

关 键 词：肝肿瘤 谐波 局灶性占位病变 射频消融治疗 肝脏恶性肿瘤 超声造影诊断 治疗适应证 实时超声 病理检查 增强CT 手术治疗 造影显示 病灶范围 手术标本 肝脏肿瘤 治疗范围 引导穿刺 疗效监测 准确性 敏感性 特异性 大直径 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]