美兰防龋的动物实验研究  

A animal experimental study on methylene blue to dental caries prevention

作　　者：王成龙[1] 刘洪臣[1] 储冰峰[1] 常平[1] 陈颖萍[1] 阎黎津[1] 

机构地区：[1]中国人民解放军总医院口腔科,北京100853

出　　处：《临床口腔医学杂志》2005年第7期403-404,共2页Journal of Clinical Stomatology

摘　　要：目的:动物实验观察美兰预防龋齿的效果,为美兰预防龋齿的临床研究提供实验依据。方法:采用Keyes龋齿评分法观察美兰对SpraagueDawley大鼠磨牙龋的预防效果。结果:在E级龋损和Ds级龋损级别中,美兰组与蒸馏水组比较相差非常显著(P<0.01),与氟化钠组相差不显著(P>0.05);Dm级龋损仅见于蒸馏水组,美兰组及氟化钠组均未发生;Dx级龋损在三组中均未出现。结论:美兰能够减少SpraagueDawley大鼠磨牙龋的发生。Objective:To study the effect of methylene blue on dental caries prevention of experimental animal, and provide experimental evidence for clinic application of methylene blue on dental caries prevention. Method:Keyes method was used to evaluate the effect of methylene blue on Spraague-Dawley mouse dental caries.Result:In E and Ds class, there are significantly different between methylene blue group and the control group (P<0.01), but no significantly different between methylene blue group and NaF group(P>0.05); Dm class was only found in the control group; Dx class was not found in all three groups.Conclusion:Methylene blue can reduce Spraague-Dawley mouse dental caries.

关 键 词：美兰 动物实验 龋齿 预防 

分 类 号：R782.2[医药卫生—口腔医学]