磷酸钙骨水泥/聚肽共聚物生物复合材料力学性能及微观结构  

Mechanical Property and Microstructure of Biological Material of Calcium Phosphate Cement/Polypeptide Copolymer

作　　者：章苏宁[1] 林嘉平[1] 陈涛[1] 刘昌胜[1] 

机构地区：[1]华东理工大学材料科学与工程学院,上海200237

出　　处：《高等学校化学学报》2005年第7期1375-1377,M011,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:50273011);教育部博士学科点基金(批准号:20010251008);上海市科学技术委员会纳米专项基金(批准号:0352nm109)资助.

摘　　要：Polypeptide graft copolymers such as poly(γ-benzyl-L-glutamate)(PBLG)-poly(ethylene glycol)(PEG) and poly(γ-ethyl-L-glutamate)(PELG)-poly(ethylene glycol)(PEG) were introduced into self-setting calcium phosphate cement(CPC) system to improve its mechanical properties. The compression strength was improved considerably by the induction of polypeptide copolymers. It is about 22.3 higher for PBLG-g-PEG and 65.0 higher for PELG-g-PEG, respectively. The results also show that for the same polypeptide copolymer, higher compression strength of composites can be obtained by introducing copolymer micelles into the CPC. According to the results of scanning electron microscope(SEM), the crystallite shapes of CPC depend on the weight fraction of polypeptide copolymer in the composites.Polypeptide graft copolymers such as poly(γ-benzyl-L-glutamate)(PBLG)-poly(ethylene glycol)(PEG) and poly(γ-ethyl-L-glutamate)(PELG)-poly(ethylene glycol)(PEG) were introduced into self-setting calcium phosphate cement(CPC) system to improve its mechanical properties. The compression strength was improved considerably by the induction of polypeptide copolymers. It is about 22.3 higher for PBLG-g-PEG and 65.0 higher for PELG-g-PEG, respectively. The results also show that for the same polypeptide copolymer, higher compression strength of composites can be obtained by introducing copolymer micelles into the CPC. According to the results of scanning electron microscope(SEM), the crystallite shapes of CPC depend on the weight fraction of polypeptide copolymer in the composites.

关 键 词：聚肽共聚物 磷酸钙骨水泥 生物复合材料 

分 类 号：TB3[一般工业技术—材料科学与工程] TQ172[化学工程—水泥工业]