涎腺腺样囊性癌银染核仁形成区的定量研究  

QUANTITATIVE ANALYSIS OF AgNOR ADENOID CYSTIC CARCINOMA OF SALIVARY GLAND

作　　者：沈丽佳[1] 陈嘉铭[1] 蔡国藩[1] 郑佩娥[1] 

机构地区：[1]暨南大学医学院口腔系,暨南大学医学院病理教研室

出　　处：《暨南大学学报（自然科学与医学版）》1994年第4期33-36,共4页Journal of Jinan University(Natural Science & Medicine Edition)

摘　　要：采用ＡｇＮＯＲ技术对３０例正常涎腺及涎腺良、恶性肿瘤中银染核仁形成区（ＡｇＮＯＲ）进行定量研究，结果显示正常涎腺ＡｇＮＯＲ计数值最低，颗粒较均一；良性肿瘤的ＡｇＮＯＲ计数值低于恶性肿瘤，大颗粒所占的比例较大。筛孔型涎腺腺样囊性癌（ＡＣＣ－Ⅰ）与团块型（ＡＣＣ－Ⅱ）其ＡｇＮＯＲ计数值存在显著性差异（Ｐ＜０．０１），这提示筛孔型ＡＣＣ细胞分化较好，属低度恶肿瘤，预后较好；实性团块型ＡＣＣ细胞分化较差，属高度恶性肿疤，预后较差，ＡｇＮＯＲ染色技术可用为判断涎腺腺样囊性癌（ＡＣＣ）恶性程度的辅助手段。Thirty cases,of normal salivary glands and benign & malignant salivary gland tumors werequantified with the AgNOR staining technique The result showed that the mean number ofAgNOR in normal salicary glands was the lowest and in benign tumors was lower thanmalignant tumors,The mean number of AgNOR possessed signficant difference between theglandular pattern of the ACC and the solid pattern of the ACC,These resIults suggested thatthe glandular pattern of the ACC may be considered as low grade maligance,It manifests a betterprognosis than the solid ones. AgNOR staining technique may be used as a diagnostic aid injudgment of the degree of malignancy of ACC in the salivary glands。

关 键 词：涎腺肿瘤 腺样囊性癌 AGNOR染色 

分 类 号：R739.87[医药卫生—肿瘤]